The purpose of this study was to investigate the mineral induction capacity in vitro of
polyanionic proteins covalently bound to a surface. Rat dentin γ-carboxyglutamate …

This is a review of the chemistry and structure of synthetic, mineral, and biologic
hydroxyapatites. Bone apatite has a large, reactive specific-surface and is characterized by …

Amorphous calcium phosphate (ACP) was transformed at 25° to hydroxyapatite (HA) in
horse and bovine serum; solutions of serum-protein fractions in tris-HCl buffer (pH 7.4), and …

X-Ray diffraction and spectrophotometric analysis have been used to investigate the role of
zinc on hydroxylapatite (HA) crystallization. The presence of zinc in solution strongly inhibits …

Acidic matrix macromolecules, present in many mineralized tissues, including those of
vertebrates, are thought to be involved in controlling crystal formation. Little, however, is …

Bone, which is formed by the infusion of an We have long known from X-ray powder
diforganic matrix, principally collagen, with calcium fractometry that the principal constituent …

Osteopontin is a phosphorylated sialoprotein containing a conserved sequence of
contiguous aspartic acid residues. This protein is expressed at high levels in mineralized …

The kinetics of growth of hydroxyapatite has been studied at 25° C and at constant
physiological pH by seeding stable supersaturated calcium phosphate solutions with …

We report selection and characterization of hydroxyapatite-binding heptapeptides from a
peptide− phage library and demonstrate the effects of two peptides, with different binding …

The constant-composition technique has been used tostudy the crystal growth of
hydroxyapatite (Ca6 (P04) 3, HAP) on HAP seed crystals at low sustained supersaturation …