Antiphospholipid antibodies: laboratory and pathogenetic aspects

PG Vlachoyiannopoulos, M Samarkos… - Critical reviews in …, 2007 - Taylor & Francis
Antiphospholipid antibodies (aPL) constitute a heterogeneous group of autoantibodies that
share the ability to bind phospholipids (PL) alone, protein-PL complexes, or PL-binding …

Antiphospholipid antibodies: lessons from the bench

T Koike, M Bohgaki, O Amengual, T Atsumi - Journal of autoimmunity, 2007 - Elsevier
Antiphospholipid antibodies (aPL) are an heterogeneous group of circulating
immunoglobulins arising in a wide range of infectious and autoimmune diseases. Since the …

Antigen specificity and clinical relevance of antiphospholipid syndrome-related autoantibodies

RR Forastiero, ME Martinuzzo - Current Rheumatology …, 2005 - ingentaconnect.com
The presence of antiphospholipid antibodies (aPL) combined with venous or arterial
thrombosis, and/or obstetric complications defines the antiphospholipid syndrome (APS) …

The clinical relevance of noncriteria antiphospholipid antibodies

ML Bertolaccini, G Sanna - Seminars in Thrombosis and …, 2018 - thieme-connect.com
While lupus anticoagulant (LA), anticardiolipin antibodies (aCL), anti-β 2 glycoprotein I (anti-
β 2 GPI) antibodies represent the best available and the most widely used tests in the …

An overview of laboratory testing for antiphospholipid antibodies

EJ Favaloro, L Pasalic - Hemostasis and Thrombosis: Methods and …, 2023 - Springer
Antiphospholipid antibodies (aPL) represent a group of autoantibodies directed against
phospholipids. These antibodies may arise in a number of autoimmune conditions, of which …

Which are the best biological markers of the antiphospholipid syndrome?

LO Carreras, RR Forastiero, ME Martinuzzo - Journal of autoimmunity, 2000 - Elsevier
The diagnosis of antiphospholipid syndrome (APS) requires the presence of both clinical
and biological features. Due to the heterogeneity of anti-phospholipid antibodies (aPL) the …

Revisiting antiphospholipid antibodies: from targeting phospholipids to phospholipid binding proteins.

ML Bertolaccini, GR Hughes, MA Khamashta - Clinical laboratory, 2004 - europepmc.org
The antiphospholipid syndrome (APS) is a multi-system prothrombotic disorder associated
with circulating auto-antibodies directed against various phospholipid-binding proteins. The …

Antiphospholipid antibodies: predictive value of laboratory tests

M Galli, G Finazzi, T Barbui - Thrombosis and haemostasis, 1997 - thieme-connect.com
Venous and arterial thromboses are the most clinically relevant manifestations of the
Antiphospholipid S yndrome (APS)(1), whose laboratory hallmark is represented by the …

Antiphospholipid syndrome,“the best prophet of the future”

O Amengual, T Atsumi - Modern rheumatology, 2018 - academic.oup.com
The antiphospholipid syndrome (APS) is an autoimmune disorder characterized by the
occurrence of venous and arterial thromboses, often multiple, and obstetric-related adverse …

Laboratory testing and identification of antiphospholipid antibodies and the antiphospholipid syndrome: a potpourri of problems, a compilation of possible solutions

EJ Favaloro, RCW Wong - Seminars in thrombosis and …, 2008 - thieme-connect.com
The antiphospholipid syndrome (APS) is an autoimmune condition characterized by
vascular thromboses and/or pregnancy morbidity, and its diagnosis currently requires …