The rat is widely used for modeling human spinal cord injury (SCI) and paraplegia.
However, quadruped animals adapt trunk, forelimb and hindlimb movements to compensate …

Granulocyte colony-stimulating factor (G-CSF) inhibits programmed cell death and
stimulates neuronal progenitor differentiation. Neuronal stem cells transplanted into injured …

Spinal cord injuries result in the loss of motor and sensory functions controlled by neurons
located at the site of the lesion and below. We hypothesized that experimentally enhanced …

Spinal cord injury (SCI) triggers a complex cellular response at the injury site, leading to the
formation of a dense scar tissue. Despite this local tissue remodeling, the consequences of …

Traumatic spinal cord injury (SCI) causes serious disruption of neuronal circuits that leads to
motor functional deficits. Regeneration of disrupted circuits back to their original target is …

Spinal cord injury (SCI) results in neural loss and consequently motor and sensory
impairment below the injury. There are currently no effective therapies for the treatment of …

The aim of this study was to systematically determine the spatial distribution of
oligodendrocytes (CC1+) and glial progenitor cells (NG2+) throughout the ventral lateral …

The capacity for long-distance axon regeneration and functional recovery after spinal cord
injury in the adult has long been thought to be a unique feature of certain non-mammalian …

Spinal cord injury (SCI) is a devastating disorder that has a poor prognosis of recovery.
Animal models of SCI are useful to understand the pathophysiology of SCI and the potential …

The initial mechanical damage of a spinal cord injury (SCI) triggers a progressive secondary
injury cascade, which is a complicated process integrating multiple systems and cells. It is …