Axonal outgrowth and Erk1/2 activation by training after spinal cord injury in rats

MJ Oh, TB Seo, KB Kwon, SJ Yoon, DJ Elzi… - Journal of …, 2009 - liebertpub.com
Physical training in experimental animals can improve locomotor activity via the regulation of
spinal neural circuitry or peripheral nerve regeneration. Here we investigated the effects of …

The fate of proliferating cells in the injured adult spinal cord

DM McTigue, FR Sahinkaya - Stem Cell Research & Therapy, 2011 - Springer
Endogenous cell proliferation and gliogenesis have been extensively documented in spinal
cord injury, particularly in terms of proliferating oligodendrocyte progenitor cells. Despite the …

Chronically increased ciliary neurotrophic factor and fibroblast growth factor‐2 expression after spinal contusion in rats

RB Tripathi, DM McTigue - Journal of Comparative Neurology, 2008 - Wiley Online Library
Demyelination and oligodendrocyte loss following spinal cord injury (SCI) are well
documented. Recently, we showed oligodendrocyte progenitor cell (OPC) accumulation and …

Changes in spinal cord injury–induced gene expression in rat are strain-dependent

C Schmitt, GS Miranpuri, VK Dhodda, J Isaacson… - The Spine Journal, 2006 - Elsevier
BACKGROUND AND CONTEXT: The functional recovery of animals subject to experimental
spinal cord injury (SCI) is dependent on the injury model as well as the species and strain of …

Three Growth Factors Induce Proliferation and Differentiation of Neural Precursor Cells In Vitro and Support Cell‐Transplantation after Spinal Cord Injury In Vivo

A Younsi, G Zheng, M Scherer, L Riemann… - Stem Cells …, 2020 - Wiley Online Library
Stem cell therapy with neural precursor cells (NPCs) has the potential to improve
neuroregeneration after spinal cord injury (SCI). Unfortunately, survival and differentiation of …

Dorsal root ganglion axons facilitate and guide cortical neural outgrowth: In vitro modeling of spinal cord injury axonal regeneration

ZX Xu, A Albayar, JP Dollé, G Hansel… - Restorative …, 2020 - content.iospress.com
Background: Spinal cord injury (SCI) patients represent a heterogeneous group, with
injuries ranging from partial compression to complete transection. Patients with complete …

Viability-dependent promoting action of adult neural precursors in spinal cord injury

D Bottai, L Madaschi, AM Di Giulio, A Gorio - Molecular medicine, 2008 - Springer
The aim of the study was the assessment of the effects of adult neural stem cell (NSC)
transplantation in a mouse model of spinal cord injury (SCI). The contusion injury was …

Cell survival or cell death: differential vulnerability of long descending and thoracic propriospinal neurons to low thoracic axotomy in the adult rat

ACC Steencken, I Smirnov, DJ Stelzner - Neuroscience, 2011 - Elsevier
Previous studies show that most short thoracic propriospinal (TPS; T5–T7) and long
descending propriospinal tract (LDPT; C4–C6) neurons are lost following low-thoracic spinal …

Contrasting neuropathology and functional recovery after spinal cord injury in developing and adult rats

Q Yuan, H Su, K Chiu, W Wu, ZX Lin - Neuroscience bulletin, 2013 - Springer
Conflicting findings exist regarding the link between functional recovery and the regrowth of
spinal tracts across the lesion leading to the restoration of functional contacts. In the present …

Transplantation of human glial restricted progenitors and derived astrocytes into a contusion model of spinal cord injury

Y Jin, B Neuhuber, A Singh, J Bouyer… - Journal of …, 2011 - liebertpub.com
Transplantation of neural progenitors remains a promising therapeutic approach to spinal
cord injury (SCI), but the anatomical and functional evaluation of their effects is complex …