Cerebral small vessel disease (SVD), which is highly age-related, is the most common
neuroimaging finding in community-dwelling elderly individuals. In addition to increasing the …

Objective To investigate whether midlife atherosclerosis is associated with different
dementia subtypes and related underlying pathologies. Methods Participants comprised the …

Recent epidemiological and clinico-pathological data indicate considerable overlap
between cerebrovascular disease (CVD) and Alzheimer's disease (AD) and suggest …

Background and purpose Whilst there is evidence implicating small vessel cerebrovascular
disease in the pathogenesis of Alzheimer's disease (AD), its specific contribution to the …

Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …

We investigated progression and interrelationships of cerebral small vessel disease (cSVD)
markers. This population-based cohort study included 325 participants (age≥ 60 years) …

Importance Identifying asymptomatic individuals at high risk of impending cognitive decline
because of Alzheimer disease is crucial for successful prevention of dementia. Vascular risk …

The occurrence of microvascular and small macrovascular lesions and Alzheimer's disease
(AD)-related pathology in the aging human brain is a well-described phenomenon. Although …

The understanding of how cerebrovascular disease (CVD) contributes to dementia is
hampered by a lack of agreed and validated pathologic methods to accord weight to the …

Accumulating evidence implicates small vessel cerebrovascular disease, visualized as
white matter hyperintensities (WMH) on T2-weighted magnetic resonance imaging, in the …