Reconsidering harbingers of dementia: progression of parietal lobe white matter hyperintensities predicts Alzheimer's disease incidence
AM Brickman, LB Zahodne, VA Guzman… - Neurobiology of …, 2015 - Elsevier
Accumulating evidence implicates small vessel cerebrovascular disease, visualized as
white matter hyperintensities (WMH) on T2-weighted magnetic resonance imaging, in the …
white matter hyperintensities (WMH) on T2-weighted magnetic resonance imaging, in the …
Current pathophysiological concepts in cerebral small vessel disease
F Rincon, CB Wright - Frontiers in aging neuroscience, 2014 - frontiersin.org
The association between cerebral small vessel disease (SVD)–in the form of white matter
lesions, infarctions, and hemorrhages–with vascular cognitive impairment (VCI), has mostly …
lesions, infarctions, and hemorrhages–with vascular cognitive impairment (VCI), has mostly …
METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: An initiative of the Joint Programme for …
M Dichgans, J Wardlaw, E Smith, V Zietemann… - Alzheimer's & …, 2016 - Elsevier
Dementia is a global problem and major target for health care providers. Although up to 45%
of cases are primarily or partly due to cerebrovascular disease, little is known of these …
of cases are primarily or partly due to cerebrovascular disease, little is known of these …
Baseline predictors of cognitive decline in patients with cerebral small vessel disease
AM Pavlovic, T Pekmezovic, G Tomic… - Journal of …, 2014 - content.iospress.com
Introduction: Cerebral small vessel disease (SVD) is a common cause of cognitive
impairment and vascular dementia. Objective: We aimed to investigate predictors of …
impairment and vascular dementia. Objective: We aimed to investigate predictors of …
Complex profiles of cerebrovascular disease pathologies in the aging brain and their relationship with cognitive decline
Background and Purpose: Cerebrovascular disease (CVD) pathologies including vessel
disease (atherosclerosis, arteriolosclerosis, and cerebral amyloid angiopathy) and tissue …
disease (atherosclerosis, arteriolosclerosis, and cerebral amyloid angiopathy) and tissue …
Cerebral amyloid and hypertension are independently associated with white matter lesions in elderly
JA Scott, MN Braskie, D Tosun… - Frontiers in aging …, 2015 - frontiersin.org
In cognitively normal (CN) elderly individuals, white matter hyperintensities (WMH) are
commonly viewed as a marker of cerebral small vessel disease (SVD). SVD is due to …
commonly viewed as a marker of cerebral small vessel disease (SVD). SVD is due to …
Associations of vascular risk and amyloid burden with subsequent dementia
Objective Midlife vascular risk factors (MVRFs) are associated with incident dementia, as are
amyloid β (Aβ) deposition and neurodegeneration. Whether vascular and Alzheimer disease …
amyloid β (Aβ) deposition and neurodegeneration. Whether vascular and Alzheimer disease …
Memory decline in elderly with cerebral small vessel disease explained by temporal interactions between white matter hyperintensities and hippocampal atrophy
EMC van Leijsen, J Tay, IWM van Uden… - …, 2019 - Wiley Online Library
White matter hyperintensities (WMH) constitute the visible spectrum of cerebral small vessel
disease (SVD) markers and are associated with cognitive decline, although they do not fully …
disease (SVD) markers and are associated with cognitive decline, although they do not fully …
[HTML][HTML] Total MRI load of cerebral small vessel disease and cognitive ability in older people
Cerebral small vessel disease (SVD) may cause cognitive dysfunction. We tested the
association between the combined presence of magnetic resonance imaging (MRI) features …
association between the combined presence of magnetic resonance imaging (MRI) features …
[HTML][HTML] Frailty and dementia risks in asymptomatic cerebral small vessel disease: a longitudinal cohort study
Objectives Frailty has been shown to predict adverse outcomes in several diseases. We
aimed to evaluate the associations between frailty profiles, both severity and subtype, and …
aimed to evaluate the associations between frailty profiles, both severity and subtype, and …