Accumulating evidence implicates small vessel cerebrovascular disease, visualized as
white matter hyperintensities (WMH) on T2-weighted magnetic resonance imaging, in the …

The association between cerebral small vessel disease (SVD)–in the form of white matter
lesions, infarctions, and hemorrhages–with vascular cognitive impairment (VCI), has mostly …

Dementia is a global problem and major target for health care providers. Although up to 45%
of cases are primarily or partly due to cerebrovascular disease, little is known of these …

Introduction: Cerebral small vessel disease (SVD) is a common cause of cognitive
impairment and vascular dementia. Objective: We aimed to investigate predictors of …

Background and Purpose: Cerebrovascular disease (CVD) pathologies including vessel
disease (atherosclerosis, arteriolosclerosis, and cerebral amyloid angiopathy) and tissue …

In cognitively normal (CN) elderly individuals, white matter hyperintensities (WMH) are
commonly viewed as a marker of cerebral small vessel disease (SVD). SVD is due to …

Objective Midlife vascular risk factors (MVRFs) are associated with incident dementia, as are
amyloid β (Aβ) deposition and neurodegeneration. Whether vascular and Alzheimer disease …

White matter hyperintensities (WMH) constitute the visible spectrum of cerebral small vessel
disease (SVD) markers and are associated with cognitive decline, although they do not fully …

Cerebral small vessel disease (SVD) may cause cognitive dysfunction. We tested the
association between the combined presence of magnetic resonance imaging (MRI) features …

Objectives Frailty has been shown to predict adverse outcomes in several diseases. We
aimed to evaluate the associations between frailty profiles, both severity and subtype, and …