Estrogen receptor alpha (ERα) is a well-established prognostic marker in breast cancer. The
role of estrogen receptor beta (ERβ) in breast cancers is still under investigation. We aimed …

The expression of estrogen receptor-α (ER-α) and related genes has emerged as one of the
major determinants of molecular classification of invasive breast cancers. Expression of a …

A comment on this article appears in" Estrogen receptor: a never ending story?" J Clin
Oncol. 2011 Aug 1; 29 (22): 2955-8. This is a comment on" Immunohistochemical detection …

Abstract Backgound and Objectives Although more than five variant forms of estrogen
receptor‐β (ERβ) have been identified, their role has not been identified. This study was …

Five isoforms of estrogen receptor beta (ER-B) have been cloned, and were shown to have
different amino acid sequences at their ligand binding domains. The aim of this study was to …

Purpose: Previous conflicting results about the prognostic significance of estrogen receptor
(ER)-β in breast cancer may be explained by contribution of isoforms, of which five exist. Our …

The recent discovery of a second estrogen receptor (ER), designated ERβ, raises pressing
questions about its role in estrogen regulation of human breast cancer cells and its …

Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) belong to a superfamily of
nuclear receptors called steroid hormone receptors, which, upon binding ligand, dimerize …

It has been shown that the risk of breast cancer developing in certain morphologically
identifiable benign breast lesions correlates with expression of estrogen receptor alpha (ER …

The role of estrogen receptor alpha (ERα) in breast cancer has been studied extensively,
and its protein expression is prognostic and a primary determinant of endocrine sensitivity …