Expression and regulation of estrogen receptor beta in human breast tumors and cell lines.

EA Vladusic, AE Hornby… - Oncology …, 2000 - spandidos-publications.com
Expression of estrogen receptor beta (ER-beta) and its regulation by estradiol and anti-
estrogens was analyzed in breast cancer cells. We determined that ER-beta is expressed in …

Immunohistochemical detection of ERβ in breast cancer: towards more detailed receptor profiling?

GP Skliris, PJ Carder, MRJ Lansdown… - British journal of cancer, 2001 - nature.com
Oestrogen receptor (ER) is used routinely to predict endocrine responsiveness in patients
with breast cancer. A second ER, ERβ has been described but its significance remains …

Quantification of estrogen receptor α and β expression in sporadic breast cancer

I Bièche, B Parfait, I Laurendeau, I Girault, M Vidaud… - Oncogene, 2001 - nature.com
The recent cloning of a second estrogen receptor (ER), designated ERβ, has prompted a
reevaluation of the role of ERs in breast cancer. We have developed and validated a real …

Decreased expression of estrogen receptor β protein in proliferative preinvasive mammary tumors

P Roger, ME Sahla, S Mäkelä, JA Gustafsson… - Cancer research, 2001 - AACR
To understand the significance of estrogen receptor β (ERβ) in mammary carcinogenesis,
we evaluated the expression of ERβ in preinvasive mammary tumors. The percentage of …

Role of estrogen receptor β in gynecological cancer

J Häring, S Schüler, C Lattrich, O Ortmann… - Gynecologic …, 2012 - Elsevier
Estrogen receptor β is expressed in normal and neoplastic ovarian and endometrial tissues.
Recent studies indicate that levels of this receptor decline in ovarian tumorigenesis, like in …

Expression of estrogen receptor-β in human breast tumors

H Dotzlaw, E Leygue, PH Watson… - The Journal of Clinical …, 1997 - academic.oup.com
The expression of a recently described novel estrogen receptor, ER-β, was detected in
several human breast tumor biopsy samples and several human breast epithelial cell lines …

The role of estrogen receptor beta in breast cancer

Y Zhou, X Liu - Biomarker research, 2020 - Springer
Breast cancer, a malignant tumor originating from mammary epithelial tissue, is the most
common cancer among women worldwide. Challenges facing the diagnosis and treatment …

Estrogen receptors in breast carcinogenesis and endocrine therapy

B Huang, M Warner, JÅ Gustafsson - Molecular and cellular endocrinology, 2015 - Elsevier
Excessive exposure to estrogen has long been associated with an increased risk for
developing breast cancer and anti-estrogen therapy is the gold standard of care in the …

Oestrogen receptors β1 and βcx have divergent roles in breast cancer survival and lymph node metastasis

G Rosin, J De Boniface, GM Karthik, J Frisell… - British journal of …, 2014 - nature.com
Background: The expression of oestrogen receptor (ER) α characterises a subset of breast
cancers associated with good response to endocrine therapy. However, the clinical …

Distinct expression patterns of ERα and ERβ in normal human mammary gland

V Speirs, GP Skliris, SE Burdall… - Journal of clinical …, 2002 - jcp.bmj.com
Aim: Two oestrogen receptors (ERs) have been identified to date—the “classic” ERα and the
more recently described ERβ. Although much is known about ERα at the mRNA and protein …