Expression of estrogen receptor beta isoforms in human breast cancer tissues and cell lines

D Tong, E Schuster, M Seifert, K Czerwenka… - Breast cancer research …, 2002 - Springer
Estrogen receptor alpha (ER-α) is an important regulator of growth and differentiation in the
mammary gland and the female reproductive tract. It is also involved in the development of …

Clinical significance of estrogen receptor β in breast and prostate cancer from biological aspects

Y Omoto, H Iwase - Cancer science, 2015 - Wiley Online Library
Breast and prostate cancers are among the most common of all cancers. They are referred
to as hormone‐dependent cancers, because estrogen and androgen are involved in their …

Evaluation of seven oestrogen receptor β antibodies for immunohistochemistry, western blotting, and flow cytometry in human breast tissue

GP Skliris, AT Parkes, JL Limer… - The Journal of …, 2002 - Wiley Online Library
Two oestrogen receptors, ERα and ERβ, exist. While much is known about ERα, the role of
ERβ is still undefined, especially at the protein level. The aim of this study was to determine …

Estrogen receptor β is expressed in human stomach adenocarcinoma

S Matsuyama, Y Ohkura, H Eguchi… - Journal of cancer …, 2002 - Springer
Purpose. In stomach adenocarcinoma, the role of the hormonal receptor, estrogen receptor
(ER), has been controversial. Recently, a new estrogen receptor, called estrogen receptor β …

Is oestrogen receptor-β a predictor of endocrine therapy responsiveness in human breast cancer?

LC Murphy, PH Watson - Endocrine-related cancer, 2006 - erc.bioscientifica.com
The role of oestrogen receptor (ER) β in human breast cancer remains unclear. However, it
is now apparent that when considering ER β in human breast cancer it is important to …

Cytoplasmic estrogen receptor in breast cancer

AW Welsh, DR Lannin, GS Young, ME Sherman… - Clinical Cancer …, 2012 - AACR
Purpose: In addition to genomic signaling, it is accepted that estrogen receptor-α (ERα) has
nonnuclear signaling functions, which correlate with tamoxifen resistance in preclinical …

Altered expression pattern of alternatively spliced estrogen receptor β transcripts in breast carcinoma

I Girault, C Andrieu, S Tozlu, F Spyratos, I Bièche… - Cancer letters, 2004 - Elsevier
Dysregulation of total estrogen receptor β (ERβ) expression has been implicated in breast
tumorigenesis. The ERβ gene yields five exon 8 alternatively spliced transcripts (ERβ1–5) …

A divergent role for estrogen receptor-beta in node-positive and node-negative breast cancer classified according to molecular subtypes: an observational prospective …

F Novelli, M Milella, E Melucci, A Di Benedetto… - Breast Cancer …, 2008 - Springer
Introduction Estrogen receptor-alpha (ER-α) and progesterone receptor (PgR) are
consolidated predictors of response to hormonal therapy (HT). In contrast, little information …

Molecular action of the estrogen receptor and hormone dependency in breast cancer

H Iwase - Breast Cancer, 2003 - Springer
The measurement of estrogen receptor (ER) α in breast cancer tissues is important to
discriminate between the hormone dependent and independent tumors. Recently, a second …

Comprehensive assessment of estrogen receptor beta antibodies in cancer cell line models and tissue reveals critical limitations in reagent specificity

AW Nelson, AJ Groen, JL Miller, AY Warren… - Molecular and cellular …, 2017 - Elsevier
Estrogen Receptor-β (ERβ) has been implicated in many cancers. In prostate and breast
cancer its function is controversial, but genetic studies implicate a role in cancer …