[HTML][HTML] High circulating SDF-1and MCP-1 levels and genetic variations in CXCL12, CCL2 and CCR5: Prognostic signature of immune recovery status in treated HIV …

E Yeregui, C Viladés, P Domingo, A Ceausu… - …, 2020 - thelancet.com
Background The underlying mechanisms of incomplete immune reconstitution in treated HIV-
positive patients are very complex and may be multifactorial, but perturbation of chemokine …

[HTML][HTML] The combination of CXCL9, CXCL10 and CXCL11 levels during primary HIV infection predicts HIV disease progression

X Yin, Z Wang, T Wu, M Ma, Z Zhang, Z Chu… - Journal of Translational …, 2019 - Springer
Background Chemokines are small chemotactic cytokines involved in inflammation, cell
migration, and immune regulation in both physiological and pathological contexts. Here, we …

Impact of CCR2 and SDF1 Polymorphisms on Disease Progression in HIV‐Infected Subjects in Thailand

P Ammaranond, S Sanguansitthianan… - Journal of Clinical …, 2013 - Wiley Online Library
Background The genotypic polymorphisms of CCR5, CCR2, and SDF1 were analyzed to
determine their impact as potential confounders with regard to disease progression because …

[HTML][HTML] CXCL13 as a biomarker of immune activation during early and chronic HIV infection

V Mehraj, R Ramendra, S Isnard, FP Dupuy… - Frontiers in …, 2019 - frontiersin.org
Background: CXCL13 is preferentially secreted by Follicular Helper T cells (TFH) to attract B
cells to germinal centers. Plasma levels of CXCL13 have been reported to be elevated …

High CXCL10/IP-10 levels are a hallmark in the clinical evolution of the HIV infection

JM Valverde-Villegas, RM de Medeiros… - Infection, Genetics and …, 2018 - Elsevier
The aim of this study was to investigate the modulation of plasma CXCL10, CCL20, CCL22,
CCL2, CCL17 and CCL24 levels in HIV-positive patients grouped according to extreme …

[HTML][HTML] CCR5 genotype and pre-treatment CD4+ T-cell count influence immunological recovery of HIV-positive patients during antiretroviral therapy

WHV Carvalho-Silva, JL Andrade-Santos… - Gene, 2020 - Elsevier
This study was performed to assess the association of CCR5Δ32 and SDF1-3′ A
polymorphisms with immunological recovery failure and to investigate the influence of …

[HTML][HTML] Increased plasma levels of the TH2 chemokine CCL18 associated with low CD4+ T cell counts in HIV-1-infected patients with a suppressed viral load

P Malhotra, P Haslett, B Sherry, DH Shepp, P Barber… - Scientific reports, 2019 - nature.com
The chemokine (CC motif) chemokine ligand 18 (CCL18) is a structural homolog of CCL3
primarily produced by monocyte-derived cells with an M2 phenotype. Elevated levels of …

[HTML][HTML] The number of CCR5 expressing CD4+ T lymphocytes is lower in HIV-infected long-term non-progressors with viral control compared to normal progressors: a …

H Meijerink, AR Indrati, R van Crevel, I Joosten… - BMC infectious …, 2014 - Springer
Background The HIV co-receptors CXCR4 and CCR5 play an important role in HIV infection
and replication. Therefore we hypothesize that long-term non-progressors (LTNP) with viral …

CCR5 and CXCR4 expression on memory and naive T cells in HIV-1 infection and response to highly active antiretroviral therapy

JKA Nicholson, SW Browning, RL Hengel… - JAIDS Journal of …, 2001 - journals.lww.com
Objective: To measure CCR5 and CXCR4 chemokine receptor expression on CD4 and CD8
T cells in HIV-1 infection and to relate levels to the distribution of CD45RO memory and …

Analysis of CCR5 and SDF‐1 genetic variants and HIV infection in Indian population

A Gupta, H Padh - International journal of immunogenetics, 2015 - Wiley Online Library
HIV‐1 infection and progression exhibits interindividual variation. The polymorphism in the
chemokine receptors CCR 5 and CXCR 4, the principal coreceptors for HIV‐1 and their …