Cerebrospinal fluid CXCL10 is associated with the presence of low level CSF HIV during suppressive antiretroviral therapy
Surrogate markers of HIV central nervous system (CNS) persistence are needed because
direct HIV measurements from the CNS require specialized protocols and are not always …
direct HIV measurements from the CNS require specialized protocols and are not always …
Risk for HIV-1 infection associated with a common CXCL12 (SDF1) polymorphism and CXCR4 variation in an African population
Abstract CXC chemokine ligand 12 (CXCL12), or stromal cell-derived factor 1 (SDF1), is the
only known natural ligand for the HIV-1 coreceptor, CXC chemokine receptor 4 (CXCR4). A …
only known natural ligand for the HIV-1 coreceptor, CXC chemokine receptor 4 (CXCR4). A …
[HTML][HTML] People with HIV have higher percentages of circulating CCR5+ CD8+ T cells and lower percentages of CCR5+ regulatory T cells
LE van Eekeren, V Matzaraki, Z Zhang… - Scientific Reports, 2022 - nature.com
CCR5 is the main HIV co-receptor. We aimed to (1) compare CCR5 expression on immune
cells between people living with HIV (PLHIV) using combination antiretroviral therapy …
cells between people living with HIV (PLHIV) using combination antiretroviral therapy …
CCR5 and CXCR4 chemokine receptor expression and β‐chemokine production during early T cell repopulation induced by highly active anti‐retroviral therapy
Giovannetti, Ensoli, Mazzetta… - Clinical & …, 1999 - Wiley Online Library
Expression of chemokine receptors and β‐chemokine production by peripheral blood
mononuclear cells (PBMC) were determined in HIV‐1‐infected individuals before and after …
mononuclear cells (PBMC) were determined in HIV‐1‐infected individuals before and after …
CXCR6 gene characterization in two ethnically distinct South African populations and association with viraemic disease control in HIV-1-infected black South African …
ACP Picton, M Paximadis, RE Chaisson… - Clinical …, 2017 - Elsevier
CXCR6 genetic variation was described for HIV-1-uninfected black (n= 41) and Caucasian
(n= 40) South Africans. We also investigated the CXCR6 rs2234358 and rs2234355 single …
(n= 40) South Africans. We also investigated the CXCR6 rs2234358 and rs2234355 single …
Distribution of HIV/AIDS protective SDF1, CCR5 and CCR2 gene variants within Cretan population
S Apostolakis, S Baritaki, E Krambovitis… - Journal of clinical …, 2005 - Elsevier
An interesting finding in the epidemiology of human immunodeficiency virus (HIV) infection
is that certain mutations in genes coding for chemokine receptors and their ligands may …
is that certain mutations in genes coding for chemokine receptors and their ligands may …
Selective Expansion of Pro-inflammatory Chemokine CCL2-Loaded CD14+CD16+ Monocytes Subset in HIV-Infected Therapy Naïve Individuals
AW Ansari, D Meyer-Olson, RE Schmidt - Journal of clinical immunology, 2013 - Springer
We have previously demonstrated the critical role of CC chemokine CCL2 in HIV-1
pathogenesis, and circulating monocytes as the major source of CCL2. Since the functional …
pathogenesis, and circulating monocytes as the major source of CCL2. Since the functional …
Stromal-derived factor-1 chemokine gene variant is associated with the delay of HIV-1 disease progression in two longitudinal cohorts
CS Dezzutti, PC Guenthner, TA Green, OJ Cohen… - Aids, 2000 - journals.lww.com
HIV-1 disease is multifactorial and is associated with a spectrum of clinical outcomes among
infected persons [1]. Viral and host factors influence HIV-1 disease progression. Chemokine …
infected persons [1]. Viral and host factors influence HIV-1 disease progression. Chemokine …
[HTML][HTML] Dichotomous Roles of Programmed Cell Death 1 on HIV-Specific CXCR5+ and CXCR5− CD8+ T Cells during Chronic HIV Infection
YM Jiao, HG Yang, HH Huang, B Tu, SJ Xing… - Frontiers in …, 2017 - frontiersin.org
Background CXCR5+ CD8+ T cells have been demonstrated to play an important role in the
control of chronic viral replication; however, the relationship between CXCR5+ CD8+ T cells …
control of chronic viral replication; however, the relationship between CXCR5+ CD8+ T cells …
[HTML][HTML] The role of CXCL13 in antibody responses to HIV-1 infection and vaccination
Y Bekele Feyissa, F Chiodi, Y Sui… - Frontiers in …, 2021 - frontiersin.org
CXCL13 signals through the G protein-coupled chemokine receptor CXCR5 to drive
development of secondary lymphoid tissue as well as B cell and Tfh cell trafficking to …
development of secondary lymphoid tissue as well as B cell and Tfh cell trafficking to …