Cytogenetic aberrations are often involved in acute myeloid leukemia (AML) and can serve
as diagnostic markers, prognosis predictors and impact the choice of therapy. A …

The reciprocal translocation t (7; 12)(q36; p13) gives rise to acute myeloid leukemia (AML) in
infants and very young children. A fusion transcript MNX1:: ETV6 is sometimes detected and …

Abstract The t (7; 12)(q36; p13)(MNX1/ETV6) is not included in the WHO classification but
has been described in up to 30% of acute myeloid leukemia (AML) in children< 2 years and …

11q23/MLL rearrangements are frequently detected in pediatric acute myeloid leukemia.
The analysis of their clinical significance is difficult because of the multitude of translocation …

To study the prognostic relevance of rare genetic aberrations in acute myeloid leukemia
(AML), such as t (16; 21), international collaboration is required. Two different types of t (16; …

The presence of chromosomal abnormalities is one of the most important criteria for
leukaemia diagnosis and management. Infant leukaemia is a rare disease that affects …

Background: Gene fusions are a frequent event in acute myeloid leukaemia (AML). It is
estimated that about 40% of AML patients harbour a cytogenetic abnormality resulting in a …

Abstract 538 The cytogenetic subgroup t (6; 9)(p22; q34), previously often reported as a
breakpoint in 6p23, is defined as a distinct entity in the 2008 WHO classification of acute …

Acute myeloid leukemia (AML) patients with t (8; 16)(p11. 2; p13) constitute a small
subgroup with a distinct genetic and clinical profile. We present a unique case of a female …

Background Acute myeloid leukemia (AML) with specific balanced 5q33 translocations are
classified as AML with myelodysplasia-related changes regardless of their morphologic …