Lymphoid stromal cells are best known as the architectural cells of lymphoid organs. For
decades, they have been considered as inert elements of the immune system but this view …

The lymphoid tissues are characterized by a complex organized architecture that is
supported by a network of stromal cells. These stromal cells play many important roles in …

Lymph nodes (LN s) are secondary immune organs dispersed throughout the body. They
are primarily composed of lymphocytes,“transient passengers” that are only present for a few …

The secondary lymphoid organs (SLOs) undergo structural changes with age, which
correlates with diminishing immune responses against infectious disease. A growing body of …

The initiation of adaptive immune responses depends upon the careful maneuvering of
lymphocytes and antigen into and within strategically placed lymph nodes (LNs). Non …

Lymph nodes are strategically located throughout the body to allow lymphocytes to
efficiently encounter their cognate antigen and become activated. The structure of the lymph …

Lymph nodes (LNs) are strategically positioned at dedicated sites throughout the body to
facilitate rapid and efficient immunity. Central to the structural integrity and framework of LNs …

Lymph node stromal cells coordinate the adaptive immune response in secondary lymphoid
organs, providing both a structural matrix and soluble factors that regulate survival and …

Lymphoid tissue returns to a steady state once each immune response is resolved, and
although this occurs multiple times throughout life, its structural integrity and functionality …

Within lymph nodes, non-hematopoietic stromal cells organize and interact with leukocytes
in an immunologically important manner. In addition to organizing T and B cell segregation …