The indole nucleus is an important element of many natural and synthetic molecules with
significant biological activity. This review covers some of the relevant and recent …

Background Various bioactive aromatic compounds containing the indole nucleus showed
clinical and biological applications. Indole scaffold has been found in many of the important …

ABSTRACT A large number of efforts were made to synthesize different heterocyclic
compounds and their derivatives in the past decade and were found to posses promising …

Heterocyclic compounds play a significant role in various biological processes of the human
body and many of them are in clinical use due to their diverse, chemical and biological …

Indoles constitute extensively explored heterocyclic ring systems with wide range of
applications in pathophysiological conditions that is, cancer, microbial and viral infections …

Heterocyclic compounds are those cyclic compounds in which one or more of the ring
carbons are replaced by another atom. The non-carbon atoms in such rings are referred to …

Indole is a versatile pharmacophore, a privileged scaffold and an outstanding heterocyclic
compound with wide ranges of pharmacological activities due to different mechanisms of …

Indoles continue to be of great interest to the pharmaceutical industry and at the current time
several thousand specific new derivatives are reported annually. Research has been driven …

The indole scaffold is found in a wide range of bioactive heterocycles and natural products.
Moreover, the indole moiety is considered as the active principle in several alkaloids such …

Heterocycles are a privileged motif that appears as a momentous objective in medicinal
chemistry. An important class of compounds for drug discovery and design is indole and its …