HMSC‐derived exosome inhibited Th2 cell differentiation via regulating miR‐146a‐5p/SERPINB2 pathway
Background. Allergic rhinitis (AR) is a global disease without specific treatment. Human
mesenchymal stem cell‐(HMSC‐) derived exosomes (HMSC‐exos) have been implicated …
mesenchymal stem cell‐(HMSC‐) derived exosomes (HMSC‐exos) have been implicated …
Intranasal delivery of MSC-derived exosomes attenuates allergic asthma via expanding IL-10 producing lung interstitial macrophages in mice
J Ren, Y Liu, Y Yao, L Feng, X Zhao, Z Li… - International …, 2021 - Elsevier
Mesenchymal stem cells (MSCs) have been investigated in preventing and treating allergic
asthma in many reports. Recently, MSC-derived exosomes (MSC-Exo) were showed a …
asthma in many reports. Recently, MSC-derived exosomes (MSC-Exo) were showed a …
Exosome miR-223-3p in the bone marrow-derived mesenchymal stem cells alleviates the inflammation and airway remodeling through NLRP3-induced ASC/Caspase …
X Li, N Yang - International Immunopharmacology, 2023 - Elsevier
Asthma is one of the most common chronic respiratory diseases in the world. Exploration
and understanding of the pathogenesis of epithelial-mesenchymal transition in airway …
and understanding of the pathogenesis of epithelial-mesenchymal transition in airway …
Adipose-derived mesenchymal stem cell-derived exosomal miR-301a-3p regulates airway smooth muscle cells during asthma by targeting STAT3
CY Feng, SY Bai, ML Li, JY Zhao, JM Sun… - Journal of Asthma …, 2022 - Taylor & Francis
Background Asthma is a chronic inflammatory disease featured by inflammation and
remodeling of airway. Adipose-derived mesenchymal stem cell (ADSCs)-derived exosomal …
remodeling of airway. Adipose-derived mesenchymal stem cell (ADSCs)-derived exosomal …
Mesenchymal stem cell exosomes promote immunosuppression of regulatory T cells in asthma
Y Du, Y Zhuansun, R Chen, L Lin, Y Lin, J Li - Experimental Cell Research, 2018 - Elsevier
Mesenchymal stem cells (MSCs) and regulatory T cells (Tregs) are both potent immune-
modulators. The aberrant proliferation and function of Tregs plays an important role in the …
modulators. The aberrant proliferation and function of Tregs plays an important role in the …
[HTML][HTML] MicroRNA-370 carried by M2 macrophage-derived exosomes alleviates asthma progression through inhibiting the FGF1/MAPK/STAT1 axis
C Li, C Deng, T Zhou, J Hu, B Dai, F Yi… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Emerging evidence has suggested the functions of exosomes in allergic diseases including
asthma. By using a mouse model with asthma induced by ovalbumin (OVA), we explored the …
asthma. By using a mouse model with asthma induced by ovalbumin (OVA), we explored the …
[HTML][HTML] MSCs exosomal miR-1470 promotes the differentiation of CD4+ CD25+ FOXP3+ Tregs in asthmatic patients by inducing the expression of P27KIP1
Y Zhuansun, Y Du, F Huang, L Lin, R Chen… - International …, 2019 - Elsevier
Abstract Exosomes derived from Mesenchymal Stem Cells (MSCs) possesses similar
immunomodulatory effect as MSCs. It had been suggested that MSCs exosomes contain …
immunomodulatory effect as MSCs. It had been suggested that MSCs exosomes contain …
Small extracellular vesicles derived from human mesenchymal stromal cells prevent group 2 innate lymphoid cell-dominant allergic airway inflammation through …
SB Fang, HY Zhang, C Wang, BX He… - Journal of …, 2020 - Taylor & Francis
Group 2 innate lymphoid cells (ILC2s) are recently reported to play a more critical role in
allergic diseases. We previously identified that mesenchymal stromal cells (MSCs) elicited …
allergic diseases. We previously identified that mesenchymal stromal cells (MSCs) elicited …
Exosome derived from human umbilical cord mesenchymal cell exerts immunomodulatory effects on B cells from SLE patients
Y Zhao, W Song, Z Yuan, M Li, G Wang… - Journal of …, 2023 - Wiley Online Library
Background. Excessive proliferation and activation of B cells, resulting in the production of
various autoantibodies, is a crucial link and significant feature of the pathogenesis of …
various autoantibodies, is a crucial link and significant feature of the pathogenesis of …
Protective effect of miR‐138‐5p inhibition modified human mesenchymal stem cell on ovalbumin‐induced allergic rhinitis and asthma syndrome
H Tang, X Han, T Li, Y Feng… - Journal of Cellular and …, 2021 - Wiley Online Library
The objective of the study is to evaluate the protective effects of human mesenchymal stem
cells (hMSCs) modified with miR‐138‐5p inhibitor against the allergic rhinitis and asthma …
cells (hMSCs) modified with miR‐138‐5p inhibitor against the allergic rhinitis and asthma …