[图书][B] Mechanisms of Amiodarone and N-desethylamiodarone Toxicity in Lung Cells
MW Bolt - 2002 - library-archives.canada.ca
Amiodarone (AM) is a potent antidysrhythmic agent that causes life-threatening pulmonary
fibrosis. Susceptibilities of different hamster lung cell types to AM-induced cytotoxicity were …
fibrosis. Susceptibilities of different hamster lung cell types to AM-induced cytotoxicity were …
Disruption of mitochondrial function and cellular ATP levels by amiodarone and N-desethylamiodarone in initiation of amiodarone-induced pulmonary cytotoxicity
MW Bolt, JW Card, WJ Racz, JF Brien… - Journal of Pharmacology …, 2001 - ASPET
Amiodarone (AM), a potent antidysrhythmic agent, can cause potentially life-threatening
pulmonary fibrosis. In the present investigation of mechanisms of initiation of AM lung …
pulmonary fibrosis. In the present investigation of mechanisms of initiation of AM lung …
[HTML][HTML] Amiodarone induces apoptosis of human and rat alveolar epithelial cells in vitro
R Bargout, A Jankov, E Dincer… - … of Physiology-Lung …, 2000 - journals.physiology.org
The antiarrhythmic amiodarone (AM) and its metabolite desethylamiodarone (Des) are
known to cause AM-induced pulmonary toxicity, but the mechanisms underlying this …
known to cause AM-induced pulmonary toxicity, but the mechanisms underlying this …
Mechanisms of amiodarone and desethylamiodarone cytotoxicity in nontransformed human peripheral lung epithelial cells
JE Mulder, JF Brien, WJ Racz, T Takahashi… - … of Pharmacology and …, 2011 - ASPET
Amiodarone (AM) is a potent antidysrhythmic agent that can cause potentially life-
threatening pulmonary fibrosis, and N-desethylamiodarone (DEA), an AM metabolite, may …
threatening pulmonary fibrosis, and N-desethylamiodarone (DEA), an AM metabolite, may …
Cytotoxic interaction between amiodarone and desethylamiodarone in human peripheral lung epithelial cells
FC Roth, JE Mulder, JF Brien, T Takahashi… - Chemico-biological …, 2013 - Elsevier
The potent and efficacious anti-dysrhythmic agent amiodarone (AM) can cause potentially
life-threatening lung damage (amiodarone-induced pulmonary toxicity; AIPT), which is …
life-threatening lung damage (amiodarone-induced pulmonary toxicity; AIPT), which is …
Effects of vitamin E on cytotoxicity of amiodarone and N-desethylamiodarone in isolated hamster lung cells
MW Bolt, WJ Racz, JF Brien, TE Massey - Toxicology, 2001 - Elsevier
Amiodarone (AM) is a potent and efficacious antidysrhythmic agent that can cause
potentially life-threatening pulmonary fibrosis. Vitamin E has been demonstrated to …
potentially life-threatening pulmonary fibrosis. Vitamin E has been demonstrated to …
[PDF][PDF] Mechanisms of Amiodarone and Desethylamiodarone Cytotoxicity in Human Lung Cells
JE Black - Master of Science thesis, 2009 - qspace.library.queensu.ca
Amiodarone (AM) is a potent antidysrhythmic agent which can cause potentially
lifethreatening pulmonary fibrosis, and N-desethylamiodarone (DEA) is a metabolite of AM …
lifethreatening pulmonary fibrosis, and N-desethylamiodarone (DEA) is a metabolite of AM …
Comparison of the in vivo pulmonary toxicity of amiodarone and des-oxo-amiodarone in the hamster
E Rafeiro, RG Leeder, JF Brien, GW Kabalka… - Toxicology and applied …, 1994 - Elsevier
Amiodarone (AM) is an effective antidysrhythmic agent, the use of which is limited because
of the drug′ s potential for causing life-threatening pulmonary fibrosis. Oxidative stress …
of the drug′ s potential for causing life-threatening pulmonary fibrosis. Oxidative stress …
[图书][B] An investigation of mechanisms in the pathogenesis of amiodarone-induced pulmonary toxicity.
E Rafeiro - 1998 - library-archives.canada.ca
Amiodarone (AM) is an efficacious antidysrhythmic agent. However, its clinical use is limited
by life-threatening pulmonary toxicity. The morphological effects of AM on cultured lung …
by life-threatening pulmonary toxicity. The morphological effects of AM on cultured lung …
Investigation of the mechanism of amiodarone-induced pulmonary toxicity.
RG Leeder - 1996 - elibrary.ru
Amiodarone (AM) is an effective antidysrhythmic agent, restricted in use by the development
of pulmonary toxicity. An animal model of fibrosis resulting from systemic AM administration …
of pulmonary toxicity. An animal model of fibrosis resulting from systemic AM administration …