Effects of Trichostatin A on the Timing of the First Cleavage and In Vitro Developmental Potential of Bovine Somatic Cell Nuclear Transfer Embryos

S Akagi, K Matsukawa - Cellular Reprogramming, 2022 - liebertpub.com
This study examined the relationship between the timing of the first cleavage and in vitro
development of bovine somatic cell nuclear transfer (SCNT) embryos treated with …

48 EFFECTS OF TRICHOSTATIN A ON DEVELOPMENT OF BOVINE SOMATIC CELL NUCLEAR TRANSFER EMBRYOS

D Iwamoto, K Saeki, S Kishigami… - Reproduction …, 2007 - CSIRO Publishing
Although cloning by somatic cell nuclear transfer (SCNT) has been achieved in various
mammalian species, its efficiency has been very low (Han et al. 2003 Theriogenology 59, 33 …

[HTML][HTML] Effects of trichostatin A on in vitro development of porcine embryos derived from somatic cell nuclear transfer

YI Jeong, CH Park, HS Kim, YW Jeong… - … journal of animal …, 2013 - ncbi.nlm.nih.gov
Many different approaches have been developed to improve the efficiency of animal cloning
by somatic cell nuclear transfer (SCNT), one of which is to modify histone acetylation levels …

43 SHORT-AND LONG-LASTING EFFECTS OF TRICHOSTATIN A TREATMENT OF SCNT EMBRYOS IN CATTLE

I Lagutina, R Duchi, S Colleoni… - Reproduction, Fertility …, 2010 - CSIRO Publishing
Both preimplantation and full-term development of mouse somatic cell nuclear transfer
(SCNT) embryos are significantly enhanced by treatment with trichostatin A (TSA), an …

Full-term development of gaur–bovine interspecies somatic cell nuclear transfer embryos: effect of trichostatin A treatment

K Srirattana, S Imsoonthornruksa… - … " Cloning and Stem …, 2012 - liebertpub.com
Trichostatin A (TSA) has previously been used in somatic cell nuclear transfer (SCNT) to
improve the cloning efficiency in several species, which led our team to investigate the …

37 EFFECTS OF TRICHOSTATIN A TREATMENT ON BOVINE SOMATIC CELL NUCLEAR TRANSFER EMBRYOS

AE Iager, Z Beyhan, PJ Ross, NP Ragina… - Reproduction …, 2008 - CSIRO Publishing
Faulty epigenetic reprogramming is a likely major cause of the low success rate observed in
all mammals produced through somatic cell nuclear transfer (SCNT). It has been reported …

28 EFFECT OF TRICHOSTATIN A ON IN VITRO EMBRYO DEVELOPMENT OF INTERSPECIES NUCLEAR TRANSFER EMBRYOS RECONSTRUCTED FROM CAT …

M Wittayarat, Z Namula, VV Luu, LTK Do… - Reproduction, fertility …, 2012 - CSIRO Publishing
Interspecies somatic cell nuclear transfer (iSCNT) is an invaluable tool for studying nucleus-
cytoplasm interactions and may provide an alternative for cloning endangered animals …

Trichostatin A promotes the development of bovine somatic cell nuclear transfer embryos

MJ Lee, SW Kim, HG Lee, GS Im, BC Yang… - … of Reproduction and …, 2011 - jstage.jst.go.jp
We studied the effects of trichostatin A (TSA), a histone deacetylase inhibitor, on the
development of bovine somatic cell nuclear transfer (SCNT) embryos by investigating (1) the …

Effect of Trichostatin A Treatment after Bovine Somatic Nuclear Transfer on Productions of Blastocyst and Offspring.

K Sawai, H Hirayama, A Minamihashi, T Hasizume… - 2008 - academic.oup.com
The gene transcription is a important factor in development of embryos and production of
normal offspring derived from somatic cell nuclear transfer (SCNT). Kishigami et al.(2006) …

24 EFFECT OF TREATMENT WITH TRICHOSTATIN A ON IN VITRO DEVELOPMENT OF BOVINE NUCLEAR-TRANSFERRED EMBRYOS

S Akagi, K Fukunari, K Matsukawa… - Reproduction …, 2006 - CSIRO Publishing
It has been reported that 5 or 50 nM trichostatin A (TSA) treatment after somatic cell nuclear
transfer (NT) improves the success rate of mouse cloning (Kishigami et al. 2006 Biochem …