Background Results of previous randomised trials have shown that interventions that lower
LDL cholesterol concentrations can significantly reduce the incidence of coronary heart …

BACKGROUND: Results of previous randomised trials have shown that interventions that
lower LDL cholesterol concentrations can significantly reduce the incidence of coronary …

Background Statins reduce LDL cholesterol and prevent vascular events, but their net effects
in people at low risk of vascular events remain uncertain. Methods This meta-analysis …

Background Statins reduce LDL cholesterol and prevent vascular events, but their net effects
in people at low risk of vascular events remain uncertain. Methods This meta-analysis …

The benefit of cholesterol-lowering therapy in the prevention of coronary heart disease
(CHD) is well established. The secondary prevention Scandinavian Simvastatin Survival …

Background Whether statin therapy is as effective in women as in men is debated, especially
for primary prevention. We undertook a meta-analysis of statin trials in the Cholesterol …

Background There has been debate about whether statin therapy is as effective in women
as men, especially for primary prevention. Methods Meta‐analyses were performed on data …

Background Findings of large randomised trials have shown that lowering LDL cholesterol
with statins reduces vascular morbidity and mortality rapidly, but limited evidence exists …

Background Although statin therapy reduces the risk of occlusive vascular events in people
with diabetes mellitus, there is uncertainty about the effects on particular outcomes and …

Background Lowering of LDL cholesterol with standard statin regimens reduces the risk of
occlusive vascular events in a wide range of individuals. We aimed to assess the safety and …