Prevalence and determinants of resistance mutations in HIV‐1‐infected patients exposed to integrase inhibitors in a large Italian cohort

S Modica, B Rossetti, F Lombardi, F Lagi… - HIV …, 2019 - Wiley Online Library
Objectives The aim of the study was to analyse the prevalence of integrase resistance
mutations in integrase strand transfer inhibitor (INSTI)‐experienced HIV‐1‐infected patients …

Prevalence of integrase strand transfer inhibitors resistance mutations in integrase strand transfer inhibitors-naive and-experienced HIV-1 infected patients: a single …

MA De Francesco, I Izzo, M Properzi… - AIDS research and …, 2018 - liebertpub.com
Integrase strand transfer inhibitor (InSTI) resistance rates are low. However, genotypic
resistance test (GRT) is not routinely performed in many centers. The aim of this study is to …

Resistance to integrase inhibitors: a national study in HIV-1-infected treatment-naive and-experienced patients

AG Marcelin, M Grude, C Charpentier… - Journal of …, 2019 - academic.oup.com
Objectives To describe integrase strand transfer inhibitor (INSTI) resistance profiles and
factors associated with resistance in antiretroviral-naive and-experienced patients failing an …

[HTML][HTML] Evaluation of HIV-1 integrase resistance emergence and evolution in patients treated with integrase inhibitors

R Scutari, C Alteri, I Vicenti, D Di Carlo… - Journal of Global …, 2020 - Elsevier
Objectives This study evaluated the emergence of mutations associated with integrase
strand transfer inhibitors (INSTI) resistance (INSTI-RMs) and the integrase evolution in …

Primary resistance to integrase strand-transfer inhibitors in Europe

M Casadellà, PM Van Ham… - Journal of …, 2015 - academic.oup.com
Objectives The objective of this study was to define the natural genotypic variation of the HIV-
1 integrase gene across Europe for epidemiological surveillance of integrase strand-transfer …

Lack of resistance to integrase inhibitors among antiretroviral-naive subjects with primary HIV-1 infection, 2007–2013

JD Stekler, J McKernan, R Milne, KA Tapia… - 2015 - journals.sagepub.com
Background US guidelines recommend genotyping for persons newly diagnosed with HIV
infection to identify transmitted drug resistance mutations associated with decreased …

Integrase inhibitor (INI) genotypic resistance in treatment-naive and raltegravir-experienced patients infected with diverse HIV-1 clades

T Doyle, DT Dunn… - Journal of …, 2015 - academic.oup.com
Objectives The aim of this study was to characterize the prevalence and patterns of
genotypic integrase inhibitor (INI) resistance in relation to HIV-1 clade. Methods The cohort …

Successful prevention of transmission of integrase resistance in the Swiss HIV Cohort Study

AU Scherrer, WL Yang, RD Kouyos… - The Journal of …, 2016 - academic.oup.com
The prevalence of integrase strand transfer inhibitor (INSTI)–transmitted drug resistance
(TDR) may increase with the increasing use of INSTIs. We analyzed the prevalence of INSTI …

Integrase strand transfer inhibitor (INSTI) genotypic resistance analysis in treatment-naive, INSTI free antiretroviral-experienced and INSTI-experienced Turkish …

M Sayan, FS Yildirim, S Akhan, I Karaoglan… - Current HIV …, 2022 - ingentaconnect.com
Background and Objective: Integrase strand transfer inhibitors (INSTIs) are currently the
standard of practice for first-line HIV therapy for most patients. We evaluated the mutations …

Primary resistance to integrase strand transfer inhibitors in Spain using ultrasensitive HIV-1 genotyping

M Casadellà, JR Santos… - Journal of …, 2020 - academic.oup.com
Background Transmission of resistance mutations to integrase strand transfer inhibitors
(INSTIs) in HIV-infected patients may compromise the efficacy of first-line antiretroviral …