Large-scale model quality assessment for improving protein tertiary structure prediction

R Cao, D Bhattacharya, B Adhikari, J Li… - Bioinformatics, 2015 - academic.oup.com
Motivation: Sampling structural models and ranking them are the two major challenges of
protein structure prediction. Traditional protein structure prediction methods generally use …

Critical assessment of methods of protein structure prediction (CASP)—Round XIV

A Kryshtafovych, T Schwede, M Topf… - Proteins: Structure …, 2021 - Wiley Online Library
Critical assessment of structure prediction (CASP) is a community experiment to advance
methods of computing three‐dimensional protein structure from amino acid sequence. Core …

Building a Better Fragment Library for De Novo Protein Structure Prediction

SHP de Oliveira, J Shi, CM Deane - PloS one, 2015 - journals.plos.org
Fragment-based approaches are the current standard for de novo protein structure
prediction. These approaches rely on accurate and reliable fragment libraries to generate …

CASP6 data processing and automatic evaluation at the protein structure prediction center

A Kryshtafovych, M Milostan… - Proteins: Structure …, 2005 - Wiley Online Library
We present a short overview of the system governing data processing and automatic
evaluation of predictions in CASP6, implemented at the Livermore Protein Structure …

Progress over the first decade of CASP experiments

A Kryshtafovych, Č Venclovas… - … structure, function, and …, 2005 - Wiley Online Library
CASP has now completed a decade of monitoring the state of the art in protein structure
prediction. The quality of structure models produced in the latest experiment, CASP6, has …

Pcons5: combining consensus, structural evaluation and fold recognition scores

B Wallner, A Elofsson - Bioinformatics, 2005 - academic.oup.com
Motivation: The success of the consensus approach to the protein structure prediction
problem has led to development of several different consensus methods. Most of them only …

Definition and classification of evaluation units for CASP10

TJ Taylor, CH Tai, YJ Huang, J Block… - Proteins: Structure …, 2014 - Wiley Online Library
For the 10th experiment on Critical Assessment of the techniques of protein Structure
Prediction (CASP), the prediction target proteins were broken into independent evaluation …

Assessment of CASP8 structure predictions for template free targets

M Ben‐David, O Noivirt‐Brik, A Paz… - Proteins: Structure …, 2009 - Wiley Online Library
The biennial CASP experiment is a crucial way to evaluate, in an unbiased way, the
progress in predicting novel 3D protein structures. In this article, we assess the quality of …

CASP5 assessment of fold recognition target predictions

LN Kinch, JO Wrabl, SS Krishna… - Proteins: Structure …, 2003 - Wiley Online Library
We present an overview of the fifth round of Critical Assessment of Protein Structure
Prediction (CASP5) fold recognition category. Prediction models were evaluated by using …

Protein structure prediction using Rosetta in CASP12

S Ovchinnikov, H Park, DE Kim… - Proteins: Structure …, 2018 - Wiley Online Library
We describe several notable aspects of our structure predictions using Rosetta in CASP12
in the free modeling (FM) and refinement (TR) categories. First, we had previously …