The global epidemic of obesity is accompanied by an increased prevalence of
cardiovascular disease (CVD), in particular stroke and heart attack. Dysfunctional adipose …

Cardiovascular disease (CVD) is the leading cause of death worldwide and the prevalence
of obesity and diabetes are increasing. In obesity, adipose tissue increases the secretion of …

The cardiometabolic syndrome, associated with increased cardiovascular disease risk in the
industrialized world, is estimated to affect one in four adults. Although the mechanisms …

Cardiometabolic diseases encompass those affecting the heart and vasculature as well as
other metabolic problems, such as insulin resistance, diabetes, and non-alcoholic fatty liver …

Adiponectin is an adipokine whose biosynthesis is deranged in obesity and diabetes
mellitus, predisposing to atherosclerosis. Evidence suggests that adiponectin has anti …

Adipose tissue (AT) has recently been identified as a dynamic endocrine organ secreting a
wide range of adipokines. Adiponectin is one such hormone, exerting endocrine and …

Obesity is strongly associated with metabolic and cardiovascular disorders. Adiponectin is
an adipose-derived plasma protein that is downregulated in subjects with obesity-related …

Adiponectin, a novel hormone made by fat tissue, regulates energy metabolism and
endothelial activation. Serum levels of adiponectin are reduced in conditions that are …

Adiponectin is an abundant plasma protein secreted from adipocytes that elicits protective
effects in the vasculature and myocardium. In obesity and insulin-resistant states …

Studies performed during the last decade indicate that adipose tissue is not only a site of
triglyceride storage but also an active endocrine organ which secretes many biologically …