Studies performed during the last decade indicate that adipose tissue is not only a site of
triglyceride storage but also an active endocrine organ which secretes many biologically …

Several adipocyte-secreted factors have been demonstrated to potentially link obesity,
insulin resistance, and cardiovascular disease. Among those, adiponectin is an insulin …

The adipose tissue, regardless of its role in generating and storing energy, acts as a key
player as an endocrine tissue, producing a wide scale of cytokines/hormones called …

Adiponectin is the most abundant peptide secreted by adipocytes, being a key component in
the interrelationship between adiposity, insulin resistance and inflammation. Central obesity …

Based on available data, adiponectin represents a multifaceted biomarker that may
beneficially affect atherosclerosis, inflammation and insulin resistance pathways. However …

Recent studies emphasize the role played by adiponectin in the homeostasis of adipose
tissue and in the pathogenesis of the metabolic syndrome, type 2 diabetes, and …

The increasing prevalence of diabetes and its complications heralds an alarming situation
worldwide. Obesity-associated changes in circulating adiponectin concentrations have the …

Cardiovascular disease accounts for an overwhelming proportion of the morbidity and
mortality suffered by patients with obesity and type 2 diabetes mellitus, and recent work has …

Adiponectin is a major adipocyte-secreted adipokine abundantly present in the circulation
as three distinct oligomeric complexes. In addition to its role as an insulin sensitizer …

Adiponectin is the most abundant adipose-specific protein. Its expression is reduced in
obesity, insulin resistance and type 2 diabetes, and plasma concentrations are inversely …