[PDF][PDF] Adiponectin and its role in the obesity-induced insulin resistance and related complications

M Haluzik, J Parizkova, MM Haluzik - Physiological research, 2004 - biomed.cas.cz
It is now generally accepted that adipose tissue acts as an endocrine organ producing a
number of substances with an important role in the regulation of food intake, energy …

The role of adiponectin in atherosclerosis and thrombosis

H Ekmekci, OB Ekmekci - Clinical and applied thrombosis …, 2006 - journals.sagepub.com
Obesity is a major risk factor for morbidity and mortality from cardiovascular causes.
Adiponectin has been identified recently as one of the adipocytokines with important …

Adiponectin: protection of the endothelium

KSL Lam, A Xu - Current diabetes reports, 2005 - Springer
Low levels of adiponectin, a fat-derived hormone, are found in coronary heart disease, type
2 diabetes, obesity, and other insulin-resistant states. Conversely, high adiponectin levels …

Adiponectin: a potential therapeutic target for metabolic syndrome

AA Ghadge, AA Khaire, AA Kuvalekar - Cytokine & growth factor reviews, 2018 - Elsevier
Adiponectin is an important adipocytokine secreted chiefly by fat containing adipocytes, and
plays a crucial role in glucose and lipid metabolism, inflammation and oxidative stress …

Pathophysiological significance of adiponectin

M Nishida, T Funahashi, I Shimomura - Medical molecular morphology, 2007 - Springer
Adipose tissue, which classically has been considered as an energy-storing organ, is now
viewed as a massive source of bioactive substances such as leptin, tumor necrosis factor …

Adiponectin: action, regulation and association to insulin sensitivity

AS Lihn, SB Pedersen, B Richelsen - Obesity reviews, 2005 - Wiley Online Library
Adiponectin is a novel adipocyte‐specific protein, which, it has been suggested, plays a role
in the development of insulin resistance and atherosclerosis. Although it circulates in high …

Adiponectin: Structure, physiological functions, role in diseases, and effects of nutrition

K Khoramipour, K Chamari, AA Hekmatikar, A Ziyaiyan… - Nutrients, 2021 - mdpi.com
Adiponectin (a protein consisting of 244 amino acids and characterized by a molecular
weight of 28 kDa) is a cytokine that is secreted from adipose tissues (adipokine). Available …

Adiponectin and risk of coronary heart disease in older men and women

JR Kizer, JI Barzilay, LH Kuller… - The Journal of Clinical …, 2008 - academic.oup.com
Context: Despite established insulin-sensitizing and antiatherogenic preclinical effects,
epidemiological investigations of adiponectin have yielded conflicting findings, and its …

Adiponectin/AdipoR research and its implications for lifestyle-related diseases

M Iwabu, M Okada-Iwabu, T Yamauchi… - Frontiers in …, 2019 - frontiersin.org
The number of patients with obesity continues to increase seriously worldwide. It has
become clear that, against a background of insulin resistance, obesity induces the so-called …

Adiponectin and cardiovascular risk. From pathophysiology to clinic: focus on children and adolescents

A Orlando, E Nava, M Giussani, S Genovesi - International journal of …, 2019 - mdpi.com
Adiponectin (Ad) is a cytokine produced by adipocytes that acts on specific receptors of
several tissues through autocrine, paracrine, and endocrine signaling mechanisms. Ad is …