The tachykinin peptide family certainly represents one of the largest peptide families
described in the animal organism. So far, more than 40 tachykinins have been isolated from …

Until recently substance P was regarded as the only tachykinin occurring in the vertebrate
CNS and intestine. The other known members of the peptide family were confined to the …

The tachykinin family has recently been extended by the discovery of a third tachykinin gene
encoding previously unknown mammalian tachykinins (hemokinin 1, endokinin A and …

The peptides of the tachykinin family are widely distributed within the mammalian peripheral
and central nervous systems and play a well-recognized role as excitatory …

There is an expanding repertoire of mammalian tachykinins produced by a variety of
tachykinin genes, gene splicing events and peptide processing. Novel tachykinin-binding …

Tachykinins belong to an evolutionarily conserved family of peptide neurotransmitters. The
mammalian tachykinins include substance P, neurokinin A and neurokinin B, which exert …

The primary structure of one of the bovine brain substance P precursors has shown the
existence of a second mammalian tachykinin sequence, named substance K, that is …

Current evidence indicates that there are three major mammalian tachykinins: substance P,
substance K, and neuromedin K. Investigations using in-vitro smooth muscle preparations …

After its discovery in 1931, substance P (SP) remained the only mammalian member of the
family of tachykinin peptides for several decades. Tachykinins thus refer to peptides sharing …

The existence of multiple mammalian tachykinins is now well established (for recent reviews
see 1-4). In addition to substance P (SP), mammalian tachykinins include neurokinin A …