Stem cell therapy and tissue engineering hold considerable potential for innovative and
transformative strategies to repair damaged tissue form and function. Although many …

Endogenous regeneration aims to rebuild and reinstate tissue function through enlisting
natural self-repairing processes. Promoting endogenous regeneration by reducing tissue …

Over the past two decades in situ tissue engineering has emerged as a new approach
where biomaterials are used to harness the body's own stem/progenitor cells to regenerate …

The immune system plays a crucial role during tissue repair and wound healing processes.
Biomaterials have been leveraged to assist in this in situ tissue regeneration process to …

All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

In Situ Tissue Regeneration: Host Cell Recruitment and Biomaterial Design explores the
body's ability to mobilize endogenous stem cells to the site of injury and details the latest …

Macrophages play an important role in tissue repair, regeneration, and the ability of
biomaterials to mediate these processes. Macrophages are highly plastic cells that exhibit …

Distilling complexity to advance regenerative medicine from laboratory animals to humans,
in situ regeneration will continue to evolve using biomaterial strategies to drive endogenous …

Recent research in the vaccine and immunotherapy fields has revealed that biomaterials
have the ability to activate immune pathways, even in the absence of other immune …

Conspectus A major function of the immune system is to detect threat from foreign invaders,
tissue damage, or cancer and to mount a counter response that resolves the threat, restores …