Current advances and challenges in the development of Acinetobacter vaccines

W Chen - Human vaccines & immunotherapeutics, 2015 - Taylor & Francis
Acinetobacter baumannii is a major cause of healthcare-associated infections worldwide
with high morbidity and mortality. The clinical treatment of A. baumannii infections has …

Recent Advances in the Pursuit of an Effective Acinetobacter baumannii Vaccine

PS Gellings, AA Wilkins, LA Morici - Pathogens, 2020 - mdpi.com
Acinetobacter baumannii has been a major cause of nosocomial infections for decades. The
absence of an available vaccine coupled with emerging multidrug resistance has prevented …

[HTML][HTML] Vaccines for Acinetobacter baumannii: thinking “out of the box”

F Perez, RA Bonomo - Vaccine, 2014 - ncbi.nlm.nih.gov
We are indeed fortunate that modern medicine continues to offer advancements that
promise better and longer lives. Delivering on that promise depends on our ability to …

Mapping Global Prevalence of Acinetobacter baumannii and Recent Vaccine Development to Tackle It

C Ma, S McClean - Vaccines, 2021 - mdpi.com
Acinetobacter baumannii is a leading cause of nosocomial infections that severely threaten
public health. The formidable adaptability and resistance of this opportunistic pathogen have …

[HTML][HTML] Development of immunization trials against Acinetobacter baumannii

TA Ahmad, DM Tawfik, SA Sheweita, M Haroun… - Trials in …, 2016 - Elsevier
Acinetobacter baumannii has recently crossed all lines once considered harmless, pushing
its way as a nosocomial pathogen. It had acquired resistance to almost all available …

Facing the challenges of multidrug-resistant Acinetobacter baumannii: progress and prospects in the vaccine development

NA Mat Rahim, HY Lee, U Strych… - Human Vaccines & …, 2021 - Taylor & Francis
ABSTRACT In 2017, the World Health Organization (WHO) named A. baumannii as one of
the three antibiotic-resistant bacterial species on its list of global priority pathogens in dire …

Subunit vaccines for Acinetobacter baumannii

N Yang, X Jin, C Zhu, F Gao, Z Weng, X Du… - Frontiers in …, 2023 - frontiersin.org
Acinetobacter baumannii is a gram-negative bacterium and a crucial opportunistic pathogen
in hospitals. A. baumannii infection has become a challenging problem in clinical practice …

Acinetobacter baumannii subunit vaccines: recent progress and challenges

YT Lau, HS Tan - Critical reviews in microbiology, 2024 - Taylor & Francis
Acinetobacter baumannii is a Gram-negative, opportunistic pathogen that causes
nosocomial infection with a high mortality rate in immunocompromised individuals. With the …

Identification of Novel Vaccine Candidates against Multidrug-Resistant Acinetobacter baumannii

DG Moriel, SA Beatson, DJ Wurpel, J Lipman… - PloS one, 2013 - journals.plos.org
Acinetobacter baumannii is an emerging opportunistic bacterium associated with
nosocomial infections in intensive care units. The alarming increase in infections caused by …

Non-antibiotic prevention and treatment against Acinetobacter baumannii infection: Are vaccines and adjuvants effective strategies?

Y Hu, X Zhang, S Deng, C Yue, X Jia… - Frontiers in Microbiology, 2023 - frontiersin.org
Acinetobacter baumannii (A. baumannii) is a Gram-negative opportunistic pathogen widely
attached to the surface of medical instruments, making it one of the most common pathogens …