Investigating levothyroxine use and its association with thyroid health in patients with hypothyroidism: a community pharmacy study

E Mehuys, B Lapauw, G T'Sjoen, T Christiaens… - Thyroid, 2023 - liebertpub.com
Background: To gain maximum therapeutic effect while minimizing side effects, it is
imperative for patients with hypothyroidism to use their levothyroxine (LT4) correctly, such as …

Levothyroxine treatment adequacy and formulation changes in patients with hypothyroidism: a retrospective study of real-world data from the United States

AC Bianco, Y Bao, O Antunez Flores, R Halpern, L Le… - Thyroid, 2023 - liebertpub.com
Background: The prevalence of hypothyroidism (HT) has increased over time. To assess the
effectiveness of treatment, we (1) studied thyrotropin (TSH) levels among patients receiving …

Comorbidities, concomitant medications, and diet as factors affecting levothyroxine therapy: results of the CONTROL surveillance project

M McMillan, KS Rotenberg, K Vora, AB Sterman… - Drugs in R&D, 2016 - Springer
Abstract Background The CONTROL Surveillance Project was a comprehensive patient-
based survey conducted among hypothyroid patients undergoing treatment. The primary …

Adherence to levothyroxine treatment among patients with hypothyroidism: a northeastern Italian survey

C Cappelli, R Castello, F Marini, A Paoletta… - Frontiers in …, 2018 - frontiersin.org
Background: A significant number of patients show sub-optimal adherence to levothyroxine
(LT4) therapy, mainly because they have to postpone their breakfast by at least 30 min. The …

Is a normal TSH synonymous with “euthyroidism” in levothyroxine monotherapy?

SJ Peterson, EA McAninch… - The Journal of Clinical …, 2016 - academic.oup.com
Context: Levothyroxine (LT4) monotherapy is the standard of care for hypothyroidism.
Objective: To determine whether LT4 at doses that normalize the serum TSH is associated …

Real-life practice of thyroid hormone use in hypothyroid and euthyroid patients: A detailed view from the THESIS questionnaire survey in France

C Buffet, L Belin, R Attanasio, R Negro… - Annales d' …, 2022 - Elsevier
Aim To describe practices of French physicians regarding thyroid hormone therapy, focusing
on available LT4 formulations. Material and methods Members of the French Endocrine …

Getting the levothyroxine (LT4) dose right for adults with hypothyroidism: opportunities and challenges in the use of modern LT4 preparations

U Gottwald-Hostalek, S Razvi - Current Medical Research and …, 2022 - Taylor & Francis
Lifelong treatment with levothyroxine (LT4) is the mainstay of management for individuals
with hypothyroidism. Many hypothyroid patients start LT4 treatment at a low dose (eg 25–50 …

Risk of over-and under-treatment with levothyroxine in primary care in Copenhagen, Denmark

JL La Cour, BR Medici, MK Grand… - European Journal of …, 2021 - academic.oup.com
Objective A decrease over time in thyroid stimulating hormone (TSH) levels when initiating
levothyroxine (L-T4) therapy for hypothyroidism has been reported, where treatment most …

Patients on levothyroxine replacement in the community: association between hypothyroidism symptoms, co-morbidities and their quality of life

NC Tan, RQ Chew, RC Subramanian, U Sankari… - Family …, 2019 - academic.oup.com
Introduction Patients may be symptomatic, resulting in lower quality of life (QOL), despite L-
thyroxine (LT4) therapy for hypothyroidism or having normal thyroid function. We …

Comparison of TSH levels with liquid formulation versus tablet formulations of levothyroxine in the treatment of adult hypothyroidism

D Brancato, A Scorsone, G Saura, L Ferrara, A Di Noto… - Endocrine Practice, 2014 - Elsevier
Objective A great number of factors can interfere with levothyroxine (LT4) tablet absorption,
leading to increased serum thyroid-stimulating hormone (TSH) levels and, accordingly, to …