Titration of medical therapy for heart failure with reduced ejection fraction

SJ Greene, GC Fonarow, AD DeVore… - Journal of the American …, 2019 - jacc.org
Background: Guidelines recommend that patients with heart failure with reduced ejection
fraction (HFrEF) have medical therapy titrated to target doses derived from clinical trials, as …

The Singapore heart failure outcomes and phenotypes (SHOP) study and prospective evaluation of outcome in patients with heart failure with preserved left ventricular …

R Santhanakrishnan, TP Ng, VA Cameron… - Journal of cardiac …, 2013 - Elsevier
BACKGROUND: Heart failure (HF) with preserved ejection fraction (EF) accounts for a
substantial proportion of cases of HF, and to date no treatments have clearly improved …

Trends in patients hospitalized with heart failure and preserved left ventricular ejection fraction: prevalence, therapies, and outcomes

BA Steinberg, X Zhao, PA Heidenreich, ED Peterson… - Circulation, 2012 - Am Heart Assoc
Background—Heart failure with preserved ejection fraction (EF) is a common syndrome, but
trends in treatments and outcomes are lacking. Methods and Results—We analyzed data …

Comparison of characteristics and outcomes of patients with heart failure preserved ejection fraction versus reduced left ventricular ejection fraction in an urban cohort

R Quiroz, G Doros, P Shaw, C Liang… - The American Journal of …, 2014 - Elsevier
Despite significant advances in therapies for patients with heart failure with reduced ejection
fraction (HFrEF), there are no evidence-based therapies for heart failure with preserved …

Longitudinal changes in ejection fraction in heart failure patients with preserved and reduced ejection fraction

SM Dunlay, VL Roger, SA Weston, R Jiang… - Circulation: Heart …, 2012 - Am Heart Assoc
Background—Heart failure (HF) can occur in patients with preserved (HFpEF, EF≥ 50%) or
reduced (HFrEF, EF< 50%) ejection fraction (EF), but changes in EF after HF diagnosis are …

Changes in left ventricular ejection fraction predict survival and hospitalization in heart failure with reduced ejection fraction

K Breathett, LA Allen, J Udelson, G Davis… - Circulation: Heart …, 2016 - Am Heart Assoc
Background—Left ventricular remodeling, as commonly measured by left ventricular ejection
fraction (LVEF), is associated with clinical outcomes. Although change in LVEF over time …

Change the management of patients with heart failure: Rationale and design of the CHAMP-HF registry

AD DeVore, L Thomas, NM Albert, J Butler… - American Heart …, 2017 - Elsevier
Heart failure (HF) with reduced ejection fraction (HFrEF) is a common and costly condition
that diminishes patients' health status and confers a poor prognosis. Despite the availability …

[HTML][HTML] Clinical characteristics and outcomes of heart failure with preserved ejection fraction: lessons from epidemiological studies

H Tsutsui, M Tsuchihashi-Makaya, S Kinugawa - Journal of cardiology, 2010 - Elsevier
Recent epidemiological studies have demonstrated that nearly half of all patients with heart
failure (HF) have preserved left ventricular ejection fraction (HFPEF). Compared to those …

Discriminating clinical features of heart failure with preserved vs. reduced ejection fraction in the community

JE Ho, P Gona, MJ Pencina, JV Tu… - European heart …, 2012 - academic.oup.com
Aims Heart failure (HF) is a major public health burden worldwide. Of patients presenting
with HF, 30–55% have a preserved ejection fraction (HFPEF) rather than a reduced ejection …

Frequency, predictors, and prognosis of ejection fraction improvement in heart failure: an echocardiogram-based registry study

A Ghimire, N Fine, JA Ezekowitz, J Howlett… - European heart …, 2019 - academic.oup.com
Aims To identify variables predicting ejection fraction (EF) recovery and characterize
prognosis of heart failure (HF) patients with EF recovery (HFrecEF). Methods and results …