Relation of disease pathogenesis and risk factors to heart failure with preserved or reduced ejection fraction: insights from the framingham heart study of the national …

DS Lee, P Gona, RS Vasan, MG Larson, EJ Benjamin… - Circulation, 2009 - Am Heart Assoc
Background—The contributions of risk factors and disease pathogenesis to heart failure with
preserved ejection fraction (HFPEF) versus heart failure with reduced ejection fraction …

Characteristics and prognosis of heart failure with improved compared with persistently reduced ejection fraction: A systematic review and meta-analyses

ME Jørgensen, C Andersson, RS Vasan… - European journal of …, 2018 - academic.oup.com
Aims We assessed the clinical characteristics and prognosis of chronic heart failure patients
with improved ejection fraction (HFIEF) compared with persistently reduced ejection fraction …

Prevalence and prognostic implications of longitudinal ejection fraction change in heart failure

G Savarese, O Vedin, D D'Amario, A Uijl, U Dahlström… - JACC: Heart Failure, 2019 - jacc.org
Objectives: This study sought to evaluate the incidence, the predictors, and the associations
with outcomes of changes in ejection fraction (EF) in heart failure (HF) patients. Background …

Effect of a hospital and postdischarge quality improvement intervention on clinical outcomes and quality of care for patients with heart failure with reduced ejection …

AD DeVore, BB Granger, GC Fonarow, HR Al-Khalidi… - Jama, 2021 - jamanetwork.com
Importance Adoption of guideline-directed medical therapy for patients with heart failure is
variable. Interventions to improve guideline-directed medical therapy have failed to …

Influence of patient age and sex on delivery of guideline-recommended heart failure care in the outpatient cardiology practice setting: findings from IMPROVE HF

CW Yancy, GC Fonarow, NM Albert, AB Curtis… - American heart …, 2009 - Elsevier
BACKGROUND: The influence of patient age and sex on delivery of guideline-
recommended heart failure (HF) therapies in contemporary outpatient settings has not been …

Association of prior left ventricular ejection fraction with clinical outcomes in patients with heart failure with midrange ejection fraction

A Brann, S Janvanishstaporn, B Greenberg - JAMA cardiology, 2020 - jamanetwork.com
Importance Patients categorized as having heart failure (HF) with left ventricular ejection
fraction (LVEF) in the midrange between 40% and 50%(HFmrEF) are known to be at …

Natural history of left ventricular ejection fraction in patients with heart failure

CL Clarke, GK Grunwald, LA Allen… - … Quality and Outcomes, 2013 - Am Heart Assoc
Background—Patients with heart failure (HF) are typically designated as having reduced or
preserved ejection fraction (HFREF, HFPEF) because of the importance of left ventricular …

Heart failure with preserved ejection fraction: mechanisms, clinical features, and therapies

K Sharma, DA Kass - Circulation research, 2014 - Am Heart Assoc
The clinical syndrome comprising heart failure (HF) symptoms but with a left ventricular
ejection fraction (EF) that is not diminished, eg, HF with preserved EF, is increasingly the …

Heart failure with preserved ejection fraction: treat now by treating comorbidities

SJ Shah, M Gheorghiade - Jama, 2008 - jamanetwork.com
HEART FAILURE (HF) IS A MAJOR PUBLIC HEALTH PROB-lem, with a prevalence of more
than 5 million cases and an incidence of 660 000 new cases per year in the United States …

Treatment of heart failure with normal ejection fraction: an inconvenient truth!

WJ Paulus, JJM van Ballegoij - Journal of the American College of …, 2010 - jacc.org
Despite use of similar drugs, outcomes of recent heart failure (HF) trials were frequently
neutral in heart failure with normal left ventricular ejection fraction (HFNEF) and positive in …