Noncardiac comorbidities in heart failure with reduced versus preserved ejection fraction

RJ Mentz, JP Kelly, TG von Lueder, AA Voors… - Journal of the American …, 2014 - jacc.org
Heart failure patients are classified by ejection fraction (EF) into distinct groups: heart failure
with preserved ejection fraction (HFpEF) or heart failure with reduced ejection fraction …

Physicians' guideline adherence is associated with long‐term heart failure mortality in outpatients with heart failure with reduced ejection fraction: the QUALIFY …

M Komajda, J Schöpe, S Wagenpfeil… - European Journal of …, 2019 - Wiley Online Library
Background Physicians' adherence to guideline‐recommended therapy is associated with
short‐term clinical outcomes in heart failure (HF) with reduced ejection fraction (HFrEF) …

Pathophysiology and etiology of heart failure

FL Johnson - Cardiology clinics, 2014 - cardiology.theclinics.com
Examining the etiology and underlying pathophysiology of heart failure (HF) is an often
neglected but important aspect of treating the condition. Identifying an underlying cause …

Medication dosing in outpatients with heart failure after implementation of a practice‐based performance improvement intervention: findings from IMPROVE HF

M Gheorghiade, NM Albert, AB Curtis… - Congestive Heart …, 2012 - Wiley Online Library
Eligible outpatients with heart failure (HF) and reduced left ventricular ejection fraction
(LVEF) frequently do not receive target doses of HF medications. The Registry to Improve …

Generalizability of randomized controlled trials in heart failure with reduced ejection fraction

YMF Lim, M Molnar, I Vaartjes… - … Journal-Quality of …, 2022 - academic.oup.com
Background Heart failure (HF) trials have stringent inclusion and exclusion criteria, but
limited data exist regarding generalizability of trials. We compared patient characteristics …

Heart failure with preserved ejection fraction: recent concepts in diagnosis, mechanisms and management

AB Gevaert, R Kataria, F Zannad, AJ Sauer, K Damman… - Heart, 2022 - heart.bmj.com
It is estimated that half of all patients with heart failure (HF) have HF with preserved ejection
fraction (HFpEF). Yet this form of HF remains a diagnostic and therapeutic challenge …

Heart failure care in the outpatient cardiology practice setting: findings from IMPROVE HF

GC Fonarow, CW Yancy, NM Albert… - Circulation: Heart …, 2008 - Am Heart Assoc
Background—Few data exist regarding contemporary care patterns for heart failure (HF) in
the outpatient setting. IMPROVE HF is a prospective cohort study designed to characterize …

The heart failure spectrum: time for a phenotype-oriented approach

GW De Keulenaer, DL Brutsaert - Circulation, 2009 - Am Heart Assoc
Chronic heart failure (HF) occurs at any level of left ventricular ejection fraction (LVEF).
Mostly driven by clinical trial design, HF has nevertheless been dichotomized according to …

[HTML][HTML] Comorbidities and cause-specific outcomes in heart failure across the ejection fraction spectrum: a blueprint for clinical trial design

G Savarese, C Settergren, B Schrage… - International Journal of …, 2020 - Elsevier
Background Comorbidities may differently affect treatment response and cause-specific
outcomes in heart failure (HF) with preserved (HFpEF) vs. mid-range/mildly-reduced …

Breakthroughs in the treatment of heart failure with mildly reduced and preserved ejection fraction

KM Talha, J Butler - Clinical cardiology, 2022 - Wiley Online Library
Historically, only patients with a left ventricular ejection fraction (LVEF) of less than or equal
to 40% were considered to have heart failure (HF). However, it was later found that patients …