Fat and bone in children: differential effects of obesity on bone size and mass according to fracture history

P Dimitri, JK Wales, N Bishop - Journal of Bone and Mineral …, 2010 - academic.oup.com
Fat mass predicts bone accrual in prepubertal children, but obese children have increased
fracture risk. We hypothesised that bone size and mass would vary according to prior …

[HTML][HTML] Increased fat mass is associated with increased bone size but reduced volumetric density in pre pubertal children

ZA Cole, NC Harvey, M Kim, G Ntani, SM Robinson… - Bone, 2012 - Elsevier
Recent studies have shown that obesity is associated with an increased risk of fracture in
both adults and children. It has been suggested that, despite greater bone size, obese …

Sex difference in the effect of puberty on the relationship between fat mass and bone mass in 926 healthy subjects, 6 to 18 years old

A Ackerman, JC Thornton, J Wang, RN Pierson Jr… - …, 2006 - Wiley Online Library
Objective: Understanding factors influencing bone mineral accrual is critical to optimize peak
bone mass during childhood. The epidemic of pediatric obesity and reported higher incident …

[HTML][HTML] Obesity during childhood and adolescence augments bone mass and bone dimensions

MB Leonard, J Shults, BA Wilson… - The American journal of …, 2004 - Elsevier
Background Studies of the effect of childhood obesity on bone accrual during growth have
yielded conflicting results, largely related to the failure to adequately characterize the …

[HTML][HTML] The impact of childhood obesity on skeletal health and development

P Dimitri - Journal of obesity & metabolic syndrome, 2019 - ncbi.nlm.nih.gov
Increased risk of fracture identified in obese children has led to a focus on the relationship
between fat, bone, and the impact of obesity during skeletal development. Early studies …

Obesity is not protective for bones in childhood and adolescence.

SJ Whiting - Nutrition reviews, 2002 - search.ebscohost.com
Abstract although body weight is considered to positively affect bones of children and adults,
recent studies suggest that overweight and obesity in childhood and adolescence reduce …

Body composition and bone mineral density in childhood

LB Rokoff, SL Rifas-Shiman, KM Switkowski, JG Young… - Bone, 2019 - Elsevier
Background Body mass compartments may have different directions of influence on bone
accrual. Studies of children are limited by relatively small sample sizes and typically make …

The impact of fat and obesity on bone microarchitecture and strength in children

JN Farr, P Dimitri - Calcified tissue international, 2017 - Springer
A complex interplay of genetic, environmental, hormonal, and behavioral factors affect
skeletal development, several of which are associated with childhood fractures. Given the …

Obesity is a risk factor for fracture in children but is protective against fracture in adults: a paradox

P Dimitri, N Bishop, JS Walsh, R Eastell - Bone, 2012 - Elsevier
With the rise in obesity worldwide, an important debate has developed as to whether excess
fat has a detrimental or protective effect on skeletal health in children and adults. Obese …

Bone density in the obese child: clinical considerations and diagnostic challenges

JC Kelley, N Crabtree, BS Zemel - Calcified tissue international, 2017 - Springer
The prevalence of obesity in children has reached epidemic proportions. Concern about
bone health in obese children, in part, derives from the potentially increased fracture risk …