[HTML][HTML] Role of oncogenic KRAS in the prognosis, diagnosis and treatment of colorectal cancer
G Zhu, L Pei, H Xia, Q Tang, F Bi - Molecular cancer, 2021 - Springer
Colorectal cancer (CRC) is a heterogeneous disease at the cellular and molecular levels.
Kirsten rat sarcoma (KRAS) is a commonly mutated oncogene in CRC, with mutations in …
Kirsten rat sarcoma (KRAS) is a commonly mutated oncogene in CRC, with mutations in …
[HTML][HTML] Targeting KRAS in colorectal cancer: a bench to bedside review
Colorectal cancer (CRC) is a heterogeneous disease with a myriad of alterations at the
cellular and molecular levels. Kristen rat sarcoma (KRAS) mutations occur in up to 40% of …
cellular and molecular levels. Kristen rat sarcoma (KRAS) mutations occur in up to 40% of …
[HTML][HTML] The current understanding on the impact of KRAS on colorectal cancer
M Meng, K Zhong, T Jiang, Z Liu, HY Kwan… - Biomedicine & …, 2021 - Elsevier
KRAS (kirsten rat sarcoma viral oncogene) is a member of the RAS family. KRAS mutations
are one of most dominant mutations in colorectal cancer (CRC). The impact of KRAS …
are one of most dominant mutations in colorectal cancer (CRC). The impact of KRAS …
[HTML][HTML] Prognostic and Predictive Roles of KRAS Mutation in Colorectal Cancer
AK Arrington, EL Heinrich, W Lee, M Duldulao… - International journal of …, 2012 - mdpi.com
The RAS gene family is among the most studied and best characterized of the known cancer-
related genes. Of the three human ras isoforms, KRAS is the most frequently altered gene …
related genes. Of the three human ras isoforms, KRAS is the most frequently altered gene …
[HTML][HTML] Prognostic Value of KRAS Mutations in Colorectal Cancer Patients
A Koulouridi, M Karagianni, I Messaritakis… - Cancers, 2022 - mdpi.com
Simple Summary Kirsten rat sarcoma viral oncogene homolog (KRAS)-mutated colorectal
cancer (CRC) seems to have a different biological behavior and therapeutic approach …
cancer (CRC) seems to have a different biological behavior and therapeutic approach …
[PDF][PDF] Research progress on KRAS mutations in colorectal cancer
M Cefalì, S Epistolio… - J. Cancer …, 2021 - pdfs.semanticscholar.org
The RAS gene family, responsible for signal transduction within the mitogen activated
protein kinase (MAPK) and phosphatidylinositol 3 kinase (PI3K) pathways, is frequently …
protein kinase (MAPK) and phosphatidylinositol 3 kinase (PI3K) pathways, is frequently …
[HTML][HTML] Mutant KRAS as a critical determinant of the therapeutic response of colorectal cancer
K Knickelbein, L Zhang - Genes & diseases, 2015 - Elsevier
Mutations in the KRAS oncogene represent one of the most prevalent genetic alterations in
colorectal cancer (CRC), the third leading cause of cancer-related death in the US. In …
colorectal cancer (CRC), the third leading cause of cancer-related death in the US. In …
Prevalence of KRAS G12C Mutation and Co-mutations and Associated Clinical Outcomes in Patients With Colorectal Cancer: A Systematic Literature Review
JH Strickler, T Yoshino, K Stevinson… - The …, 2023 - academic.oup.com
Purpose A systematic literature review was conducted to estimate the global prevalence of
Kirsten rat sarcoma virus gene (KRAS) mutations, with an emphasis on the clinically …
Kirsten rat sarcoma virus gene (KRAS) mutations, with an emphasis on the clinically …
Targeting RAS signaling pathway as a potential therapeutic target in the treatment of colorectal cancer
A Bahrami, SM Hassanian… - Journal of cellular …, 2018 - Wiley Online Library
The V‐Ki‐ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) is frequently
dysregulated in colorectal cancer (CRC). It is involved in the modulation of several …
dysregulated in colorectal cancer (CRC). It is involved in the modulation of several …