3-[5-{2-(2, 3-Dihydroxyprop-1-yl)-o-carboran-1-yl} pentan-1-yl] thymidine (N5-2OH) is a first
generation 3-carboranyl thymidine analog (3CTA) that has been intensively studied as a …

3-[5-{2-(2, 3-Dihydroxyprop-1-yl)-o-carboran-1-yl} pentan-1-yl] thymidine (compound 1, N5-
2OH) belongs to a novel class of boron delivery agents for neutron capture therapy, which …

Novel 3-carboranyl thymidine analogues (3CTAs) were synthesized as potential boron
delivery agents for boron neutron capture therapy (BNCT). This library includes six …

The purpose of the present study was to evaluate the effectiveness of a 3-carboranyl
thymidine analogue (3CTA), 3-[5-{2-(2, 3-dihydroxyprop-1-yl)-o-carboran-1-yl} pentan-1-yl] …

The cellular pharmacology of the D-and L-enantiomers of β-5-o-carboranyl-2′-
deoxyuridine (CDU), compounds designed for boron neutron capture therapy (BNCT), were …

Several thymidine analogues substituted with closo-and nido-carborane at the N-3 position
were synthesized. The nido-carboranyl thymidine analogues were designed to be effective …

Boron neutron capture therapy (BNCT) is a chemoradio-therapeutic method for the treatment
of cancer. It depends on the selective targeting of tumor cells by boron-containing …

The compound class of 3-carboranyl thymidine analogues (3CTAs) are boron delivery
agents for boron neutron capture therapy (BNCT), a binary treatment modality for cancer …

A library of sixteen 2nd generation amino-and amido-substituted carboranyl pyrimidine
nucleoside analogs, designed as substrates and inhibitors of thymidine kinase 1 (TK1) for …

Five novel 3-carboranyl thymidine analogues (3CTAs) were designed and synthesized for
boron neutron capture therapy (BNCT) of cancer. Phosphorylation of all five 3CTAs was …