CatSper mediates not only chemotactic behavior but also the motility of ascidian sperm
T Kijima, D Kurokawa, Y Sasakura… - Frontiers in Cell and …, 2023 - frontiersin.org
Introduction: Sperm motility, including chemotactic behavior, is regulated by changes in the
intracellular Ca2+ concentration, and the sperm-specific Ca2+ channel CatSper has been …
intracellular Ca2+ concentration, and the sperm-specific Ca2+ channel CatSper has been …
Comparative genomic analysis suggests that the sperm-specific sodium/proton exchanger and soluble adenylyl cyclase are key regulators of CatSper among the …
F Romero, T Nishigaki - Zoological Letters, 2019 - Springer
Background CatSper is a sperm-specific calcium ion (Ca 2+) channel, which regulates
sperm flagellar beating by tuning cytoplasmic Ca 2+ concentrations. Although this Ca 2+ …
sperm flagellar beating by tuning cytoplasmic Ca 2+ concentrations. Although this Ca 2+ …
CatSper1 required for evoked Ca2+ entry and control of flagellar function in sperm
AE Carlson, RE Westenbroek, T Quill… - Proceedings of the …, 2003 - National Acad Sciences
CatSper family proteins are putative ion channels expressed exclusively in membranes of
the sperm flagellum and required for male fertility. Here, we show that mouse CatSper1 is …
the sperm flagellum and required for male fertility. Here, we show that mouse CatSper1 is …
Structural evolution of CatSper1 in rodents is influenced by sperm competition, with effects on sperm swimming velocity
Background Competition between spermatozoa from rival males for success in fertilization
(ie, sperm competition) is an important selective force driving the evolution of male …
(ie, sperm competition) is an important selective force driving the evolution of male …
CatSper and sperm hyperactivation
LJ Kong, YY Yang, GL Wang - … nan ke xue= National Journal of …, 2007 - europepmc.org
Elevation of sperm Ca2+ seems to be responsible for an asymmetric form of motility called
hyperactivation, which is first seen near the time of fertilization. CatSper family proteins are …
hyperactivation, which is first seen near the time of fertilization. CatSper family proteins are …
All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility
H Qi, MM Moran, B Navarro… - Proceedings of the …, 2007 - National Acad Sciences
Mammalian spermatozoa become motile at ejaculation, but before they can fertilize the egg,
they must acquire more thrust to penetrate the cumulus and zona pellucida. The forceful …
they must acquire more thrust to penetrate the cumulus and zona pellucida. The forceful …
The Ca2+ channel CatSper is not activated by cAMP/PKA signaling but directly affected by chemicals used to probe the action of cAMP and PKA
T Wang, S Young, H Krenz, F Tüttelmann… - Journal of Biological …, 2020 - ASBMB
The sperm-specific Ca 2+ channel CatSper (cation channel of sperm) controls the influx of
Ca 2+ into the flagellum and, thereby, the swimming behavior of sperm. A hallmark of human …
Ca 2+ into the flagellum and, thereby, the swimming behavior of sperm. A hallmark of human …
A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa
JJL Chung, B Navarro, G Krapivinsky, L Krapivinsky… - Biophysical …, 2011 - cell.com
Calcium (Ca2+) signaling is critical for successful fertilization. In spermatozoa, capacitation,
hyperactivation of motility, and the acrosome reaction are mediated by changes in the …
hyperactivation of motility, and the acrosome reaction are mediated by changes in the …
CatSper: a unique calcium channel of the sperm flagellum
PV Lishko, N Mannowetz - Current opinion in physiology, 2018 - Elsevier
Highlights•In vivo, a successful fertilization is dependent on sperm hyperactivated motility.•
Hyperactivation is triggered by a calcium influx into flagellum via sperm-specific calcium …
Hyperactivation is triggered by a calcium influx into flagellum via sperm-specific calcium …