[HTML][HTML] A purification system for 64Cu produced by a biomedical cyclotron for antibody PET imaging

T Toyota, T Hanafusa, T Oda, I Koumura… - … of Radioanalytical and …, 2013 - Springer
Ion exchange is a simple and efficient method for separating no-carrier-added 64 Cu from
an irradiated Ni target. We developed a semi-automated two-round 64 Cu separation system …

Chelating ion-exchange methods for the preparation of no-carrier-added 64Cu

S Watanabe, S Watanabe, J Liang, H Hanaoka… - Nuclear medicine and …, 2009 - Elsevier
INTRODUCTION: We have developed a method for producing no-carrier-added 64Cu by
using chelating resin bearing iminodiacetic acid groups. METHODS: We optimized the …

Automated production of 64 Cu prepared by 18 MeV cyclotron

J Ometáková, P Rajec, V Csiba, M Leporis… - Journal of …, 2012 - akjournals.com
Abstract 64 Cu (T 1/2= 12, 7 h, β− 37, 1%, β+ 17, 9%, EC 41%) is a useful radioisotopes for
positron emission tomography radiopharmaceutical. We used the reaction route 64 Ni (p, n) …

Efficient preparation of high-quality 64Cu for routine use

T Ohya, K Nagatsu, H Suzuki, M Fukada… - Nuclear Medicine and …, 2016 - Elsevier
Introduction Copper-64 is an attractive radionuclide for positron emission tomography and is
emerging as a radiotherapeutic agent. The demand of 64 Cu with low metallic impurities has …

Production of 61Cu by deuteron irradiation of natural Ni

R Strangis, CG Lepera - … on Cyclotrons and …, 2007 - mdanderson.elsevierpure.com
Abstract 61 Cu (T1/2= 3.33 h, 61% β+) offers several advantages over other Cu
radioisotopes for labeling radiopharmaceuticals for positron emission tomography (PET) …

Production of no-carrier-added 64 Cu and applications to molecular imaging by PET and PETIS as a biomedical tracer

SH Watanabe, Y Iida, N Suzui, T Katabuchi… - … of radioanalytical and …, 2009 - akjournals.com
Copper-64 was produced by the 64 Ni (p, n) 64 Cu reaction using enriched 64 NiO target.
We investigated and compared the production yield of 64 Cu for proton beams of various …

Production of therapeutic quantities of 64Cu using a 12 MeV cyclotron

A Obata, S Kasamatsu, DW McCarthy, MJ Welch… - Nuclear medicine and …, 2003 - Elsevier
64Cu is a useful radiotracer for positron emission tomography (PET) and a promising
radiotherapy agent for the treatment of cancer. Recently, 64Cu-labeled …

Implementation of a new separation method to produce qualitatively improved 64Cu

NP van der Meulen, R Hasler, A Blanc… - Journal of Labelled …, 2019 - Wiley Online Library
Background 64Cu (T1/2= 12.7 h) is an important radionuclide for diagnostic purposes and
used for positron emission tomography (PET). A previous method utilized at Paul Scherrer …

PC-controlled radiochemistry system for preparation of no-carrier-added 64 Cu

R Adam Rebeles, P Van den Winkel… - … of radioanalytical and …, 2010 - akjournals.com
A homemade modular PC-controlled radiochemistry system, used to separate the no-carrier-
added 64 Cu from irradiated electroplated solid cyclotron target 64 Ni layers was developed …

Cyclotron production of using natural Zn & enriched targets

AH Asad, SV Smith, S Chan, CM Jeffery… - AIP Conference …, 2012 - pubs.aip.org
Copper-61 (61 Cu) shares with 64 Cu certain advantages for PET diagnostic imaging, but
has a shorter half-life (3.4 hr vs. 12.7 hr) and a greater probability of positron production per …