Genome-wide profiling of dysregulated piRNAs and their target genes implicated in oncogenicity of tongue squamous cell carcinoma
PIWI-interacting RNAs (piRNAs) are single-stranded, 23–36 nucleotide long RNAs that
regulate gene expression in the germline but are also detected in some cancers. However …
regulate gene expression in the germline but are also detected in some cancers. However …
HPV status is associated with altered PIWI-interacting RNA expression pattern in head and neck cancer
Objectives As HPV-induced cases of oral malignancy increase, it is important to understand
the molecular differences between HPV positive and negative head and neck squamous cell …
the molecular differences between HPV positive and negative head and neck squamous cell …
Systematic evaluation of the effects of genetic variants on PIWI-interacting RNA expression across 33 cancer types
PIWI-interacting RNAs (piRNAs) are an emerging class of non-coding RNAs involved in
tumorigenesis. Expression quantitative trait locus (eQTL) analysis has been demonstrated to …
tumorigenesis. Expression quantitative trait locus (eQTL) analysis has been demonstrated to …
Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology
Abstract Human PIWI-interacting RNAs (piRNAs) are known to be expressed in germline
cells, functionally silencing LINEs and SINEs. Their expression patterns in somatic tissues …
cells, functionally silencing LINEs and SINEs. Their expression patterns in somatic tissues …
Smoking status regulates a novel panel of PIWI-interacting RNAs in head and neck squamous cell carcinoma
Objective Smoking remains a primary etiological factor in head and neck squamous cell
carcinoma (HNSCC). Given that non-coding RNAs (ncRNAs), including PIWI-interacting …
carcinoma (HNSCC). Given that non-coding RNAs (ncRNAs), including PIWI-interacting …
Transcriptome‑wide piRNA profiling in human gastric cancer
X Lin, Y Xia, D Hu, Q Mao, Z Yu… - Oncology …, 2019 - spandidos-publications.com
Piwi‑interacting RNAs (piRNAs) comprise the largest class of non‑coding RNAs. They
represent a molecular feature shared by all non‑aging biological systems, including …
represent a molecular feature shared by all non‑aging biological systems, including …
Piwi-interacting RNAs in cancer: emerging functions and clinical utility
PIWI-interacting RNAs (piRNAs) are emerging players in cancer genomics. Originally
described in the germline, there are over 20,000 piRNA genes in the human genome. In …
described in the germline, there are over 20,000 piRNA genes in the human genome. In …
PIWI-interacting RNA 021285 is involved in breast tumorigenesis possibly by remodeling the cancer epigenome
Abstract Although PIWI-interacting RNAs (piRNAs) account for the largest class of the small
non-coding RNA superfamily, virtually nothing is known of their function in human …
non-coding RNA superfamily, virtually nothing is known of their function in human …
Emerging roles of PIWI-interacting RNAs (piRNAs) and PIWI proteins in head and neck cancer and their potential clinical implications
Head and neck squamous cell carcinoma (HNSCC) are among the well-known neoplasms
originating in the oral cavity, pharynx, and larynx. Despite advancements in chemotherapy …
originating in the oral cavity, pharynx, and larynx. Despite advancements in chemotherapy …
[HTML][HTML] Computational methods reveal novel functionalities of PIWI-interacting RNAs in human papillomavirus-induced head and neck squamous cell carcinoma
Human papillomavirus (HPV) infection is the fastest growing cause of head and neck
squamous cell carcinoma (HNSCC) today, but its role in malignant transformation remains …
squamous cell carcinoma (HNSCC) today, but its role in malignant transformation remains …