Hyperpolarized helium-3 gas magnetic resonance imaging of the lung

HU Kauczor - Topics in Magnetic Resonance Imaging, 2003 - journals.lww.com
Abstract 3 He magnetic resonance imaging (MRI) is capable of producing new and regional
information on normal and abnormal lung ventilation. The basis of 3 He MRI involves …

Elucidation of structure–function relationships in the lung: contributions from hyperpolarized 3helium MRI

HU Kauczor, B Eberle - Clinical physiology and functional …, 2002 - Wiley Online Library
Magnetic resonance imaging (MRI) using hyperpolarized 3helium (He) gas as the source of
signal provides new physiological insights into the structure–function relationships of the …

Imaging physiological parameters with hyperpolarized gas MRI

SJ Kadlecek, K Emami, MC Fischer, M Ishii, J Yu… - Progress in Nuclear …, 2005 - Elsevier
Traditional magnetic resonance imaging (MRI) uses the NMR signal from protons to obtain
images in the human body. The technique enables detailed imaging of brain and soft tissue …

Assessment of a single‐acquisition imaging sequence for oxygen‐sensitive 3He‐MRI

AJ Deninger, B Eberle, J Bermuth… - … in Medicine: An …, 2002 - Wiley Online Library
MRI of the lungs using hyperpolarized helium‐3 (3He) allows the determination of
intrapulmonary oxygen partial pressures (pO2). The need to separate competing processes …

[PDF][PDF] Real-time MR imaging of pulmonary gas-flow dynamics with hyperpolarized 3He

K Ruppert, JR Brookeman, JP Mugler - … of the 6th Annual Meeting of …, 1998 - Citeseer
MR studies of the human lung with hyperpolarized 3 He have demonstrated the potential to
acquire high-resolution, but static, images of lung ventilation [1-3]. Given the high signal …

Simultaneous measurement of pulmonary partial pressure of oxygen and apparent diffusion coefficient by hyperpolarized 3He MRI

J Yu, M Law, S Kadlecek, K Emami… - … in Medicine: An …, 2009 - Wiley Online Library
Abstract Hyperpolarized 3He (HP 3He) MRI shows promise to assess structural and
functional pulmonary parameters in a sensitive, regional, and noninvasive way. Structural …

MR tagging of human lungs using hyperpolarized 3He gas

JR Owers‐Bradley, MS Fichele… - Journal of Magnetic …, 2003 - Wiley Online Library
Purpose To evaluate the use of spin‐tagging in conjunction with hyperpolarized gas
imaging for monitoring lung ventilation and gas diffusion. Methods and Materials Images …

Imaging of lung function using hyperpolarized helium‐3 magnetic resonance imaging: review of current and emerging translational methods and applications

S Fain, ML Schiebler, DG McCormack… - Journal of magnetic …, 2010 - Wiley Online Library
During the past several years there has been extensive development and application of
hyperpolarized helium‐3 (HP 3He) magnetic resonance imaging (MRI) in clinical respiratory …

Dynamic echo planar MR imaging of lung ventilation with hyperpolarized 3He in normal subjects and patients with severe emphysema

DS Gierada, B Saam, D Yablonskiy… - NMR in Biomedicine …, 2000 - Wiley Online Library
We applied the rapid imaging capability of echo planar MR pulse sequences and
hyperpolarized 3He ventilation imaging to observe the dynamic distribution of gas in the …

Measurements of regional alveolar oxygen pressure using hyperpolarized 3He MRI1

MC Fischer, S Kadlecek, J Yu, M Ishii, K Emami… - Academic radiology, 2005 - Elsevier
RATIONALE AND OBJECTIVES: The aim of this work is to review hyperpolarized (HP)
helium-3 (3He) magnetic resonance imaging (MRI) methods to measure regional alveolar …