Spatial and topological distribution of progesterone receptor A and B isoforms during human development

T Inoue, J Akahira, J Takeyama, T Suzuki… - Molecular and Cellular …, 2001 - Elsevier
Progesterone receptor (PR) is a member of the nuclear receptor superfamily. To date, two
isoforms of PR have been identified, PR-A and PR-B. In progesterone responsive tissues …

Systemic distribution of progesterone receptor subtypes in human tissues

T Asavasupreechar, R Saito, Y Miki… - The Journal of steroid …, 2020 - Elsevier
Progesterone receptor (PR) is expressed in a wide variety of human tissues, including both
reproductive and non-reproductive tissues. Upon binding to the PR, progesterone can …

Estradiol differentially induces progesterone receptor isoforms expression through alternative promoter regulation in a mouse embryonic hypothalamic cell line

ER Vázquez-Martínez, I Camacho-Arroyo… - Endocrine, 2016 - Springer
Progesterone receptor (PR) presents two main isoforms (PR-A and PR-B) that are regulated
by two specific promoters and transcribed from alternative transcriptional start sites. The …

Colocalization of progesterone receptors A and B by dual immunofluorescent histochemistry in human endometrium during the menstrual cycle

PA Mote, RL Balleine, EM McGowan… - The Journal of Clinical …, 1999 - academic.oup.com
The human progesterone receptor (PR) is expressed as two isoforms, PRA and PRB, that
function as ligand-activated transcription factors. In vitro studies suggest that the isoforms …

Overlapping and distinct expression of progesterone receptors A and B in mouse uterus and mammary gland during the estrous cycle

PA Mote, RL Arnett-Mansfield, N Gava… - …, 2006 - academic.oup.com
In rodents, progesterone receptors (PRs) A and B have different and often nonoverlapping
roles, and this study asked whether different activities of the PR proteins in mouse are …

Regional differences in expression of progesterone receptor in oviduct and uterus of rabbit during early pregnancy

SR Anzaldúa, I Camacho-Arroyo… - … and Physiology Part A …, 2007 - Elsevier
We characterized the expression pattern of progesterone receptor (PR) in two regions of the
oviduct (ampullae and isthmus), and the uterus (epithelium and stroma) of the rabbit …

Progesterone receptor expression in human decidua and fetal membranes before and after contractions: possible mechanism for functional progesterone withdrawal

S Goldman, A Weiss, I Almalah… - Molecular human …, 2005 - academic.oup.com
In humans, progesterone levels are sustained before the onset of labour. Therefore, the
mechanism for parturition that has been proposed for humans is 'functional'progesterone …

Expression of progesterone receptors A and B in the mouse ovary during the estrous cycle

N Gava, CL Clarke, K Byth, RL Arnett-Mansfield… - …, 2004 - academic.oup.com
Progesterone plays a central role in the regulation of ovarian function. The progesterone
receptor (PR) has been shown to be essential for ovulation because mice lacking PR fail to …

The cytoplasmic 60 kDa progesterone receptor isoform predominates in the human amniochorion and placenta at term

AH Taylor, PC McParland, DJ Taylor… - Reproductive Biology and …, 2009 - Springer
Background The mechanism that initiates human parturition has been proposed to
be'functional progesterone withdrawal'whereby the 116 kDa B-isoform of the progesterone …

Nuclear progesterone receptors in the human pregnancy myometrium: evidence that parturition involves functional progesterone withdrawal mediated by increased …

AA Merlino, TN Welsh, H Tan, LJ Yi… - The Journal of …, 2007 - academic.oup.com
Context: We examined whether human parturition involves functional progesterone
withdrawal mediated by changes in myometrial expression of progesterone receptors (PRs) …