Epigenetic modifications control chromatin structure and function, and thus mediate changes
in gene expression, ultimately influencing protein levels. Recent research indicates that …

Introduction Epigenetics has recently emerged as a potential mechanism by which adverse
environmental stimuli can result in persistent changes in gene expression. Epigenetic …

Major depressive disorder is one of the most common mental illnesses as it affects more
than 350 million people globally. Major depressive disorder is etiologically complex and …

Depression is a prevalent and complex psychiatric syndrome. Epigenetic mechanisms
bridge the genetic and environmental factors that contribute to the pathophysiology of …

Epigenetic modifications in response to traumatic experience and stress are emerging as
important factors in the long-term biological trajectories leading to stress-related psychiatric …

Epigenetics refers to potentially heritable processes that can mediate both lasting and
transient changes in gene expression in the absence of genome sequence alterations. The …

Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …

Epigenetic mechanisms, which control chromatin structure and function, mediate changes in
gene expression that occur in response to diverse stimuli. Recent research has established …

Environmental stressors, such as childhood maltreatment, have been recognized to
contribute to the development of depression. Growing evidence suggests that epigenetic …

The risk for major depression is both genetically and environmentally determined. It has
been proposed that epigenetic mechanisms could mediate the lasting increases in …