Strong evidence supports the existence of a discontinuation syndrome following the
withdrawal of antidepressant medication, particularly second-generation antidepressants …

Discontinuation symptoms are recognised with tricyclic antidepressants, monoamine
oxidase inhibitors, selective serotonin reuptake inhibitors (SSRIs) and miscellaneous …

A common phenomenon accompanying treatment with nearly every major class of
antidepressant is the emergence of the discontinuation syndrome in some patients. It is seen …

Antidepressant discontinuation symptoms occur with all classes of antidepressant. A well-
described discontinuation syndrome occurs with the selective serotonin reuptake inhibitors …

Background Antidepressants are among the most commonly prescribed drugs worldwide.
They are often discontinued, frequently without the knowledge of the prescribing physician. It …

To minimize the symptoms of antidepressant discontinuation, gradual tapering is necessary
for all serotonin reuptake inhibitors (SRIs) except fluoxetine, which has an extended half-life …

Depressive disorders require long-term treatment with antidepressants, psychotherapy, or
both. The goal of antidepressant therapy is complete remission of symptoms and return to …

Sudden or tapered withdrawal from treatment with antidepressants, including monoamine
oxidase inhibitors (MAOIs), tricyclic antidepressants (TCAs), and serotonin selective …

Depression is the most frequent and costly problem in primary care, where most of these
patients are seen and treated. In many countries, the public regard antidepressant drugs as …

Introduction Evidence is lacking on withdrawal syndrome related to individual
antidepressants and relevant risk factors for severe reactions. Objective To ascertain …