Maintenance therapy after quadruple induction therapy in HIV-1 infected individuals: Amsterdam Duration of Antiretroviral Medication (ADAM) study

MHE Reijers, GJ Weverling, S Jurriaans, FWNM Wit… - The Lancet, 1998 - thelancet.com
Background Highly active antiretroviral therapy (HAART) has led to health benefits for
patients infected with HIV-1. However, long-term use of multidrug regimens is difficult to …

A randomized trial of three maintenance regimens given after three months of induction therapy with zidovudine, lamivudine, and indinavir in previously untreated HIV …

G Pialoux, F Raffi, F Brun-Vezinet… - … England Journal of …, 1998 - Mass Medical Soc
Background The long-term effectiveness of potent three-drug antiretroviral regimens for the
treatment of human immunodeficiency virus type 1 (HIV-1) infection is limited by problems …

Structured treatment interruptions to control HIV-1 infection

F Lori, R Maserati, A Foli, E Seminari, J Timpone… - The Lancet, 2000 - thelancet.com
Structured treatment interruptions to control HIV-1 infection Page 1 RESEARCH LETTERS Our
results show that a single post-injury injection of autoimmune T cells directed against the CNS …

Correlation between reduction in plasma HIV-1 RNA concentration 1 week after start of antiretroviral treatment and longer-term efficacy

MA Polis, IA Sidorov, C Yoder, S Jankelevich, J Metcalf… - The Lancet, 2001 - thelancet.com
Background Early assessment of antiretroviral drug efficacy is important for prevention of the
emergence of drug-resistant virus and unnecessary exposure to ineffective drug regimens …

Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection

GK Robbins, V De Gruttola, RW Shafer… - … England Journal of …, 2003 - Mass Medical Soc
Background The optimal sequencing of antiretroviral regimens for the treatment of infection
with human immunodeficiency virus type 1 (HIV-1) is unknown. We compared several …

Mechanisms of virologic failure in previously untreated HIV-infected patients from a trial of induction-maintenance therapy

D Descamps, P Flandre, V Calvez, G Peytavin… - Jama, 2000 - jamanetwork.com
ContextIn the Trilège trial, following induction with a zidovudine, lamivudine, and indinavir
regimen, human immunodeficiency virus (HIV) replication was less suppressed by 2-drug …

Short-course antiretroviral therapy in primary HIV infection

SPARTAC Trial Investigators - New England Journal of Medicine, 2013 - Mass Medical Soc
Background Short-course antiretroviral therapy (ART) in primary human immunodeficiency
virus (HIV) infection may delay disease progression but has not been adequately evaluated …

Simultaneous vs sequential initiation of therapy with indinavir, zidovudine, and lamivudine for HIV-1 infection: 100-week follow-up

RM Gulick, JW Mellors, D Havlir, JJ Eron, C Gonzalez… - Jama, 1998 - jamanetwork.com
Context.—Combination antiretroviral therapy can markedly suppress human
immunodeficiency virus (HIV) replication but the duration of HIV suppression varies among …

Clinical progression and virological failure on highly active antiretroviral therapy in HIV-1 patients: a prospective cohort study

B Ledergerber, M Egger, M Opravil, A Telenti… - The Lancet, 1999 - thelancet.com
Background The efficacy of highly active antiretroviral therapy (HAART) in suppression of
HIV-1 is well documented. We investigated virological and clinical outcomes of HAART in …

Failures of 1 week on, 1 week off antiretroviral therapies in a randomized trial

J Ananworanich, R Nuesch, M Le Braz… - Aids, 2003 - journals.lww.com
Background: Scheduled treatment interruptions are being evaluated in an effort to decrease
costs and side effects of highly active antiretroviral therapy (HAART). A schedule of 1 week …