Intrauterine growth restriction (IUGR) impairs insulin secretion in humans and in animal
models of IUGR. Several underlying mechanisms have been implicated, including …

Intrauterine growth restriction (IUGR) has been defined in several ways, but in general
describes a condition in which the fetus exhibits poor growth in utero. This complication of …

Fetal adverse environment, such as insufficient maternal nutrition, placental insufficiency
and stress, alters organ development and leads to poor fetal growth, also called intrauterine …

Placental insufficiency is a primary cause of intrauterine growth restriction (IUGR). IUGR
increases the risk of developing type 2 diabetes mellitus (T2DM) throughout life, which …

We determined in vivo and in vitro pancreatic islet insulin secretion and glucose metabolism
in fetuses with intrauterine growth restriction (IUGR) caused by chronic placental …

The intrauterine growth restricted (IUGR) fetus develops unique metabolic adaptations in
response to exposure to reduced nutrient supply. These adaptations provide survival value …

Intrauterine growth retardation (IUGR) has been linked to the development of type 2
diabetes later in life and the mechanisms underlying this phenomena are unknown …

Intrauterine growth restriction (IUGR) represents a reduction from the physiological growth
rate. Fetal growth depends from the maternal supply of nutrients through the placenta into …

Intrauterine growth retardation (IUGR) has been linked to later development of type 2
diabetes in adulthood. Human studies indicate that individuals who were growth retarded at …

Intrauterine growth restriction (IUGR) increases the risk of type 2 diabetes developing in
adulthood. In previous studies that used bilateral uterine artery ligation in a rat model of …