Highlights•Thrombosis and excess platelet activation are key pathologic features of
pulmonary arterial hypertension (PAH).•Platelets are the main source of circulating …

Eur J Clin Invest 2012 Abstract Background The various aetiologies and risk factors for
pulmonary arterial hypertension (PAH) lead to close phenotypes with small differences …

Pulmonary hypertension (PH) is associated with platelet activation, vascular inflammation
and endothelial dysfunction leading to often life threatening thrombo-embolic complications …

Pulmonary arterial hypertension is a rare disease of the pulmonary vasculature,
characterised pathologically by proliferation, remodelling and thrombosis in situ …

Pulmonary hypertension (PH) is a fatal disease with no treatment options, characterised by
elevated pulmonary vascular resistanzce and secondary right ventricular failure. The …

Pulmonary Hypertension (PH) is a multifactorial and lethal disease, characterised by
elevated pulmonary arterial pressure and progressive right heart failure. PH pathobiology …

Pulmonary hypertension (PH) is defined by increased mean pulmonary artery pressure, and
the clinical classification includes five etiologies, of which we investigated subgroup 1 …

Rationale: Procoagulant microparticles constitute valuable hallmarks of cell damage.
Microparticles also behave as cellular effectors. Objectives: We hypothesized that the extent …

Pulmonary arterial hypertension is a multifactorial disease characterized by
vasoconstriction, vascular remodeling, inflammation and thrombosis. Although an increasing …

Background Pulmonary arterial hypertension (PAH) results from pulmonary vascular
disease and may eventually lead to right heart failure and death. Vasodilator therapy has …