Examining the potential of developing and implementing use of adiponectin-targeted therapeutics for metabolic and cardiovascular diseases
Y Liu, V Vu, G Sweeney - Frontiers in endocrinology, 2019 - frontiersin.org
Cardiometabolic diseases encompass those affecting the heart and vasculature as well as
other metabolic problems, such as insulin resistance, diabetes, and non-alcoholic fatty liver …
other metabolic problems, such as insulin resistance, diabetes, and non-alcoholic fatty liver …
Adiponectin and cardiovascular disease: mechanisms and new therapeutic approaches
G Siasos, D Tousoulis, C Kollia… - Current medicinal …, 2012 - ingentaconnect.com
Adiponectin is an abundant plasma protein secreted from adipocytes. Its role in energy
homeostasis is well-known, including the regulation of hydrocarbons and lipids metabolism …
homeostasis is well-known, including the regulation of hydrocarbons and lipids metabolism …
[HTML][HTML] Adiponectin and metabolic cardiovascular diseases: Therapeutic opportunities and challenges
X Lei, S Qiu, G Yang, Q Wu - Genes & Diseases, 2023 - Elsevier
Metabolic cardiovascular diseases have become a global health concern, and some of their
risk factors are linked to several metabolic disorders. They are the leading causes of death …
risk factors are linked to several metabolic disorders. They are the leading causes of death …
Back to the heart: the protective role of adiponectin
Cardiovascular disease (CVD) is the leading cause of death worldwide and the prevalence
of obesity and diabetes are increasing. In obesity, adipose tissue increases the secretion of …
of obesity and diabetes are increasing. In obesity, adipose tissue increases the secretion of …
Adiponectin and cardiovascular health: an update
The global epidemic of obesity is accompanied by an increased prevalence of
cardiovascular disease (CVD), in particular stroke and heart attack. Dysfunctional adipose …
cardiovascular disease (CVD), in particular stroke and heart attack. Dysfunctional adipose …
The role of adiponectin in maintaining metabolic homeostasis
Background: Adiponectin is an adipocyte-derived cytokine closely associated with obesity,
altered body adipose tissue distribution, insulin resistance, and cardiovascular diseases …
altered body adipose tissue distribution, insulin resistance, and cardiovascular diseases …
Therapeutic perspectives for adiponectin: an update
In obesity, the expansion of dysfunctional adipose tissue leads to augmented production of
pro-inflammatory adipokines that mediate metabolic changes through their paracrine and/or …
pro-inflammatory adipokines that mediate metabolic changes through their paracrine and/or …
Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies
S Shetty, CM Kusminski, PE Scherer - Trends in pharmacological sciences, 2009 - cell.com
Adiponectin is a secretory protein predominantly expressed by adipocytes and released at a
high rate into circulation. The ease with which the levels of adiponectin can be measured …
high rate into circulation. The ease with which the levels of adiponectin can be measured …
Modulation of adiponectin as a potential therapeutic strategy
S Lim, MJ Quon, KK Koh - Atherosclerosis, 2014 - Elsevier
Adiponectin is produced predominantly by adipocytes and plays an important role in
metabolic and cardiovascular homeostasis through its insulin-sensitizing actions and anti …
metabolic and cardiovascular homeostasis through its insulin-sensitizing actions and anti …
Adiponectin synthesis, secretion and extravasation from circulation to interstitial space
SC da Silva Rosa, M Liu, G Sweeney - Physiology, 2021 - journals.physiology.org
Adiponectin, an adipokine that circulates as multiple multimeric complexes at high levels in
serum, has antidiabetic, anti-inflammatory, antiatherogenic, and cardioprotective properties …
serum, has antidiabetic, anti-inflammatory, antiatherogenic, and cardioprotective properties …