White matter integrity and key structures affected in Alzheimer's disease characterized by diffusion tensor imaging

D Xiao, K Wang, L Theriault, E Charbel… - European Journal of …, 2022 - Wiley Online Library
White matter (WM) degeneration is suggested to predict the early signs of Alzheimer's
disease (AD). The exact structural regions of brain circuitry involved are not known. This …

Cognition-related white matter integrity dysfunction in Alzheimer's disease with diffusion tensor image

Y Li, F Feng, P Lin, ZG Huang, T Liu, B Zhou… - Brain Research …, 2018 - Elsevier
Alzheimer's disease (AD) is a worldwide progressive neurodegenerative disorder in the
elderly. Previous research has indicated that Alzheimer's disease impairs white matter (WM) …

Reproducible Abnormalities and Diagnostic Generalizability of White Matter in Alzheimer's Disease

Y Qu, P Wang, H Yao, D Wang, C Song, H Yang… - Neuroscience …, 2023 - Springer
Alzheimer's disease (AD) is associated with the impairment of white matter (WM) tracts. The
current study aimed to verify the utility of WM as the neuroimaging marker of AD with …

Ultrastructural hippocampal and white matter alterations in mild cognitive impairment: a diffusion tensor imaging study

A Fellgiebel, P Wille, MJ Müller, G Winterer… - Dementia and geriatric …, 2004 - karger.com
Mild cognitive impairment (MCI) is considered to be a transitional stage between normal
aging and dementia. In Alzheimer's disease (AD), white matter structural pathology is due to …

White matter changes in patients with amnestic mild cognitive impairment detected by diffusion tensor imaging

J Liu, C Yin, S Xia, L Jia, Y Guo, Z Zhao, X Li, Y Han… - PloS one, 2013 - journals.plos.org
Compared to normal aging adults, individuals with amnestic mild cognitive impairment
(aMCI) have significantly increased risk for progressing into Alzheimer's disease (AD) …

Microstructural changes in the hippocampus and posterior cingulate in mild cognitive impairment and Alzheimer's disease: a diffusion tensor imaging study

YJ Hong, B Yoon, SC Lim, YS Shim, JY Kim… - Neurological …, 2013 - Springer
Diffusion tensor imaging (DTI) is a sensitive MRI technique in the detection of white matter
degeneration. We sought to demonstrate microstructural changes in normal controls …

Longitudinal white matter changes in Alzheimer's disease: a tractography-based analysis study

S Kitamura, K Kiuchi, T Taoka, K Hashimoto, S Ueda… - Brain research, 2013 - Elsevier
Alzheimer's disease (AD) classically presents with gray matter atrophy, as well as feature
significant white matter abnormalities. Previous evidence indicates the overall burden of …

[HTML][HTML] Specific white matter tracts and diffusion properties predict conversion from mild cognitive impairment to Alzheimer's disease

DB Stone, SG Ryman, AP Hartman, CJ Wertz… - Frontiers in Aging …, 2021 - frontiersin.org
Identifying biomarkers that can assess the risk of developing Alzheimer's Disease (AD)
remains a significant challenge. In this study, we investigated the integrity levels of brain …

Different patterns of white matter degeneration using multiple diffusion indices and volumetric data in mild cognitive impairment and Alzheimer patients

GS Alves, L O'Dwyer, A Jurcoane, V Oertel-Knöchel… - PloS one, 2012 - journals.plos.org
Alzheimeŕs disease (AD) represents the most prevalent neurodegenerative disorder that
causes cognitive decline in old age. In its early stages, AD is associated with microstructural …

Diffusion tensor imaging measures of normal appearing white matter in patients who are aging, or have amnestic mild cognitive impairment, or Alzheimer's disease

JH Wang, PY Lv, HB Wang, ZL Li, N Li, ZY Sun… - Journal of Clinical …, 2013 - Elsevier
To evaluate whether cerebral white matter integrity is related to cognitive function, and
whether diffusion tensor imaging (DTI) could differentiate amnestic mild cognitive …