Leptin and incident cardiovascular disease: the Multi-ethnic Study of Atherosclerosis (MESA)

SS Martin, MJ Blaha, ED Muse, AN Qasim, MP Reilly… - Atherosclerosis, 2015 - Elsevier
Objective Higher serum leptin levels have been associated with a modestly higher incidence
of cardiovascular disease in studies involving mostly Caucasian men. We aimed to assess …

Leptin and coronary heart disease: prospective study and systematic review

N Sattar, G Wannamethee, N Sarwar… - Journal of the American …, 2009 - jacc.org
Objectives: This study sought to better determine the link between leptin and coronary heart
disease (CHD). Background: Circulating leptin is considered a risk factor for CHD but larger …

Relation of increased leptin concentrations to history of myocardial infarction and stroke in the United States population

J Sierra-Johnson, A Romero-Corral… - The American journal of …, 2007 - Elsevier
Leptin, an adipose tissue–derived hormone, has been linked to cardiovascular outcomes;
however, data are limited in the United States population, especially women. To assess the …

Association of low leptin with cardiovascular events and mortality in patients with stable coronary artery disease: the Heart and Soul Study

IA Ku, R Farzaneh-Far, E Vittinghoff, MH Zhang, B Na… - Atherosclerosis, 2011 - Elsevier
OBJECTIVE: Leptin is an adipokine with both protective and harmful effects on the
cardiovascular (CV) system. Prior studies evaluating the association between leptin and CV …

Plasma leptin and the risk of cardiovascular disease in the west of Scotland coronary prevention study (WOSCOPS)

AM Wallace, AD McMahon, CJ Packard, A Kelly… - Circulation, 2001 - Am Heart Assoc
Background—Leptin plays a role in fat metabolism and correlates with insulin resistance
and other markers of the metabolic syndrome, independent of total adiposity. Therefore, we …

Plasma leptin: associations with metabolic, inflammatory and haemostatic risk factors for cardiovascular disease

SG Wannamethee, J Tchernova, P Whincup… - Atherosclerosis, 2007 - Elsevier
BACKGROUND AND AIM: Leptin, an adipocyte-derived protein, regulating food intake and
metabolism has been implicated in the development of coronary heart disease. We have …

Leptin and coronary heart disease risk: prospective case control study of British women

DA Lawlor, GD Smith, A Kelly, N Sattar, S Ebrahim - Obesity, 2007 - Wiley Online Library
Objective: Prospective studies have shown a positive association between leptin
concentrations and coronary heart disease (CHD) in men, but its effect in women is unclear …

Leptin concentration and risk of coronary heart disease and stroke: A systematic review and meta-analysis

H Yang, W Guo, J Li, S Cao, J Zhang, J Pan, Z Wang… - PloS one, 2017 - journals.plos.org
Background and purpose Although high leptin concentration has been shown to be
correlated with established vascular risk factors, epidemiologic studies have reported …

Leptin and coronary heart disease: a systematic review and meta-analysis

SB Chai, F Sun, XL Nie, J Wang - Atherosclerosis, 2014 - Elsevier
Introduction Leptin, an adipose tissue-derived hormone, plays a central role in regulating
human energy homeostasis. The role of leptin in regulating blood pressure, activating the …

Leptinemia and its association with stroke and coronary heart disease in the Jackson Heart Study

J Liu, KR Butler, SG Buxbaum, JH Sung… - Clinical …, 2010 - Wiley Online Library
Background To examine the association of increased plasma leptin concentration with
prevalent stroke and coronary heart disease (CHD) and to examine the genetic contributions …