Maintenance of chondroitin sulfation balance by chondroitin-4-sulfotransferase 1 is required for chondrocyte development and growth factor signaling during cartilage …
Glycosaminoglycans (GAGs) such as heparan sulfate and chondroitin sulfate are
polysaccharide chains that are attached to core proteins to form proteoglycans. The …
polysaccharide chains that are attached to core proteins to form proteoglycans. The …
The roles of chondroitin-4-sulfotransferase-1 in development and disease
M Klüppel - Progress in molecular biology and translational …, 2010 - Elsevier
The glycosaminoglycan chondroitin sulfate (CS) consists of long linear chains of repeating
disaccharide units, which are covalently attached to core proteins to form CS-proteoglycans …
disaccharide units, which are covalently attached to core proteins to form CS-proteoglycans …
[HTML][HTML] An Overview of in vivo Functions of Chondroitin Sulfate and Dermatan Sulfate Revealed by Their Deficient Mice
S Mizumoto, S Yamada - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
Chondroitin sulfate (CS), dermatan sulfate (DS) and heparan sulfate (HS) are covalently
attached to specific core proteins to form proteoglycans in their biosynthetic pathways. They …
attached to specific core proteins to form proteoglycans in their biosynthetic pathways. They …
Defective proteoglycan sulfation of the growth plate zones causes reduced chondrocyte proliferation via an altered Indian hedgehog signalling
B Gualeni, M Facchini, F De Leonardis, R Tenni… - Matrix Biology, 2010 - Elsevier
Mutations in the sulfate transporter gene, SCL26A2, lead to cartilage proteoglycan
undersulfation resulting in chondrodysplasia in humans; the phenotype is mirrored in the …
undersulfation resulting in chondrodysplasia in humans; the phenotype is mirrored in the …
Heparan sulfate proteoglycans: coordinators of multiple signaling pathways during chondrogenesis
CB Kirn‐Safran, RR Gomes, AJ Brown… - … Research Part C …, 2004 - Wiley Online Library
Heparan sulfate proteoglycans are abundantly expressed in the pericellular matrix of both
developing and mature cartilage. Increasing evidence indicates that the action of numerous …
developing and mature cartilage. Increasing evidence indicates that the action of numerous …
Chondroitin 4-O-sulfotransferase-1 regulates the chain length of chondroitin sulfate in co-operation with chondroitin N-acetylgalactosaminyltransferase-2
T Izumikawa, Y Okuura, T Koike, N Sakoda… - Biochemical …, 2011 - portlandpress.com
Previously, we demonstrated that sog9 cells, a murine L cell mutant, are deficient in the
expression of C4ST (chondroitin 4-O-sulfotransferase)-1 and that they synthesize fewer and …
expression of C4ST (chondroitin 4-O-sulfotransferase)-1 and that they synthesize fewer and …
Chondroitin sulfate N-acetylgalactosaminyltransferase-1 is required for normal cartilage development
Y Watanabe, K Takeuchi, S Higa Onaga… - Biochemical …, 2010 - portlandpress.com
CS (chondroitin sulfate) is a glycosaminoglycan species that is widely distributed in the
extracellular matrix. To understand the physiological roles of enzymes involved in CS …
extracellular matrix. To understand the physiological roles of enzymes involved in CS …
Involvement of chondroitin sulfate synthase-3 (chondroitin synthase-2) in chondroitin polymerization through its interaction with chondroitin synthase-1 or chondroitin …
T Izumikawa, T Uyama, Y Okuura… - Biochemical …, 2007 - portlandpress.com
Previously, we have demonstrated that co-expression of ChSy-1 (chondroitin synthase-1),
with ChPF (chondroitin-polymerizing factor) resulted in a marked augmentation of …
with ChPF (chondroitin-polymerizing factor) resulted in a marked augmentation of …
Chondroitin sulphate and heparan sulphate sulphation motifs and their proteoglycans are involved in articular cartilage formation during human foetal knee joint …
J Melrose, MD Isaacs, SM Smith, CE Hughes… - Histochemistry and cell …, 2012 - Springer
Novel sulphation motifs within the glycosaminoglycan chain structure of chondroitin sulphate
(CS) containing proteoglycans (PGs) are associated with sites of growth, differentiation and …
(CS) containing proteoglycans (PGs) are associated with sites of growth, differentiation and …
Molecular cloning and expression of a second chondroitin N-acetylgalactosaminyltransferase involved in the initiation and elongation of chondroitin/dermatan sulfate
T Uyama, H Kitagawa, J Tanaka, J Tamura… - Journal of Biological …, 2003 - ASBMB
We identified a novel human chondroitinN-acetylgalactosaminyltransferase, designated
chondroitin GalNAcT-2 after a BLAST analysis of the GenBank TM data base using the …
chondroitin GalNAcT-2 after a BLAST analysis of the GenBank TM data base using the …