Modifiable risk factors for Alzheimer's disease

GA Edwards III, N Gamez, G Escobedo Jr… - Frontiers in aging …, 2019 - frontiersin.org
Since first described in the early 1900s, Alzheimer's disease (AD) has risen exponentially in
prevalence and concern. Research still drives to understand the etiology and pathogenesis …

Is Alzheimer's disease risk modifiable?

A Serrano-Pozo, JH Growdon - Journal of Alzheimer's disease, 2019 - content.iospress.com
Population-based clinic-pathological studies have established that the most common
pathological substrate of dementia in community-dwelling elderly people is mixed …

Alzheimer disease and its growing epidemic: risk factors, biomarkers, and the urgent need for therapeutics

RA Hickman, A Faustin, T Wisniewski - Neurologic clinics, 2016 - neurologic.theclinics.com
Alzheimer disease (AD) represents one of the greatest medical challenges of this century;
the condition is becoming increasingly prevalent worldwide and as yet, no effective …

Midlife predictors of Alzheimer's disease

BB Bendlin, CM Carlsson, CE Gleason, SC Johnson… - Maturitas, 2010 - Elsevier
Factors contributing to increased risk for Alzheimer's disease (AD) include age, sex, genes,
and family history of AD. Several risk factors for AD are endogenous; however, accumulating …

Pathogenesis of Alzheimer's disease

RH Swerdlow - Clinical interventions in aging, 2007 - Taylor & Francis
Alzheimer's disease (AD) is incredibly common. Increasing longevity ensures its prevalence
will rise even further. Ongoing efforts to understand AD pathogenesis reveal numerous …

Update on Alzheimer's disease therapy and prevention strategies

WV Graham, A Bonito-Oliva… - Annual review of …, 2017 - annualreviews.org
Alzheimer's disease (AD) is the primary cause of age-related dementia. Effective strategies
to prevent and treat AD remain elusive despite major efforts to understand its basic biology …

[HTML][HTML] Advances in the prevention of Alzheimer's Disease

S Sindi, F Mangialasche, M Kivipelto - F1000prime reports, 2015 - ncbi.nlm.nih.gov
Abstract Alzheimer's disease (AD), the leading cause of dementia, has reached epidemic
proportions, with major social, medical and economical burdens. With no currently available …

Protective genes and pathways in Alzheimer's disease: moving towards precision interventions

M Seto, RL Weiner, L Dumitrescu… - Molecular …, 2021 - Springer
Alzheimer's disease (AD) is a progressive, neurodegenerative disorder that is characterized
by neurodegeneration, cognitive impairment, and an eventual inability to perform daily tasks …

Modifiable risk factors in Alzheimer disease and related dementias: a review

R Litke, LC Garcharna, S Jiwani, J Neugroschl - Clinical therapeutics, 2021 - Elsevier
Abstract Purpose Although Alzheimer disease and related dementias (ADRDs) have long
been considered nonpreventable and even an inevitable consequence of aging, recent …

Alzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkers

C Reitz, R Mayeux - Biochemical pharmacology, 2014 - Elsevier
The global prevalence of dementia is as high as 24 million, and has been predicted to
quadruple by the year 2050. In the US alone, Alzheimer disease (AD)–the most frequent …