Advances and perspectives in near‐infrared fluorescent organic probes for surgical oncology

D Xu, L Li, C Chu, X Zhang, G Liu - Wiley Interdisciplinary …, 2020 - Wiley Online Library
Surgical resection of solid tumors is currently the most efficient and preferred therapeutic
strategy for treating cancer. Despite significant medical, technical, and scientific advances …

Next generation NIR fluorophores for tumor imaging and fluorescence-guided surgery: A review

A Haque, MSH Faizi, JA Rather, MS Khan - Bioorganic & medicinal …, 2017 - Elsevier
Cancer is a group of diseases responsible for the major causes of mortality and morbidity
among people of all ages. Even though medical sciences have made enormous growth …

Tissue-specific near-infrared fluorescence imaging

EA Owens, M Henary, G El Fakhri… - Accounts of chemical …, 2016 - ACS Publications
Conspectus Near-infrared (NIR) fluorescence light has been widely utilized in clinical
imaging by providing surgeons highly specific images of target tissue. The “NIR window” …

Quicker, deeper and stronger imaging: A review of tumor-targeted, near-infrared fluorescent dyes for fluorescence guided surgery in the preclinical and clinical stages

J Jiao, J Zhang, F Yang, W Song, D Han, W Wen… - European Journal of …, 2020 - Elsevier
Cancer is a public health problem and the main cause of human mortality and morbidity
worldwide. Complete removal of tumors and metastatic lymph nodes in surgery is …

Advancements in Intraoperative Near-Infrared Fluorescence Imaging for Accurate Tumor Resection: A Promising Technique for Improved Surgical Outcomes and …

SK Rainu, RG Ramachandran… - ACS Biomaterials …, 2023 - ACS Publications
Clear surgical margins for solid tumor resection are essential for preventing cancer
recurrence and improving overall patient survival. Complete resection of tumors is often …

A review of NIR dyes in cancer targeting and imaging

S Luo, E Zhang, Y Su, T Cheng, C Shi - Biomaterials, 2011 - Elsevier
The development of multifunctional agents for simultaneous tumor targeting and near
infrared (NIR) fluorescence imaging is expected to have significant impact on future …

Near-infrared fluorescence probes for surgical navigation

S Hameed, Z Dai - Materials today chemistry, 2018 - Elsevier
Optical imaging is a promising tool for visualizing fundamental biological processes
including disease progression, detection of tumors, and therapeutic monitoring non …

Near-infrared fluorescent probes in cancer imaging and therapy: an emerging field

X Yi, F Wang, W Qin, X Yang, J Yuan - International Journal of …, 2014 - Taylor & Francis
Near-infrared fluorescence (NIRF) imaging is an attractive modality for early cancer
detection with high sensitivity and multi-detection capability. Due to convenient modification …

New insight into the application of fluorescence platforms in tumor diagnosis: From chemical basis to clinical application

Y Li, Q Chen, X Pan, W Lu… - Medicinal Research …, 2023 - Wiley Online Library
Early and rapid diagnosis of tumors is essential for clinical treatment or management. In
contrast to conventional means, bioimaging has the potential to accurately locate and …

Beyond the margins: real-time detection of cancer using targeted fluorophores

RR Zhang, AB Schroeder, JJ Grudzinski… - Nature reviews Clinical …, 2017 - nature.com
Over the past two decades, synergistic innovations in imaging technology have resulted in a
revolution in which a range of biomedical applications are now benefiting from fluorescence …