Cloning of the Arabidopsis Clock Gene TOC1, an Autoregulatory Response Regulator Homolog

C Strayer, T Oyama, TF Schultz, R Raman, DE Somers… - Science, 2000 - science.org
The toc1 mutation causes shortened circadian rhythms in light-grown Arabidopsis plants.
Here, we report the same toc1 effect in the absence of light input to the clock. We also show …

Reciprocal Regulation Between TOC1 and LHY/CCA1 Within the Arabidopsis Circadian Clock

D Alabadı́, T Oyama, MJ Yanovsky, FG Harmon, P Más… - Science, 2001 - science.org
The interactive regulation between clock genes is central for oscillator function. Here, we
show interactions between the Arabidopsis clock genes LATE ELONGATED HYPOCOTYL …

A Functional Genomics Approach Reveals CHE as a Component of the Arabidopsis Circadian Clock

JL Pruneda-Paz, G Breton, A Para, SA Kay - Science, 2009 - science.org
Transcriptional feedback loops constitute the molecular circuitry of the plant circadian clock.
In Arabidopsis, a core loop is established between CCA1 and TOC1. Although CCA1 …

Mapping the Core of the Arabidopsis Circadian Clock Defines the Network Structure of the Oscillator

W Huang, P Pérez-García, A Pokhilko, AJ Millar… - Science, 2012 - science.org
In many organisms, the circadian clock is composed of functionally coupled morning and
evening oscillators. In Arabidopsis, oscillator coupling relies on a core loop in which the …

Targeted degradation of TOC1 by ZTL modulates circadian function in Arabidopsis thaliana

P Más, WY Kim, DE Somers, SA Kay - Nature, 2003 - nature.com
The underlying mechanism of circadian rhythmicity appears to be conserved among
organisms, and is based on negative transcriptional feedback loops forming a cellular …

Dual role of TOC1 in the control of circadian and photomorphogenic responses in Arabidopsis

P Más, D Alabadí, MJ Yanovsky, T Oyama… - The Plant …, 2003 - academic.oup.com
To examine the role of the TOC1 (TIMING OF CAB EXPRESSION1) gene in the Arabidopsis
circadian system, we generated a series of transgenic plants expressing a gradation in …

CONSTANS mediates between the circadian clock and the control of flowering in Arabidopsis

P Suárez-López, K Wheatley, F Robson, H Onouchi… - Nature, 2001 - nature.com
Flowering is often triggered by exposing plants to appropriate day lengths. This response
requires an endogenous timer called the circadian clock to measure the duration of the day …

Arabidopsis circadian clock protein, TOC1, is a DNA-binding transcription factor

JM Gendron, JL Pruneda-Paz… - Proceedings of the …, 2012 - National Acad Sciences
The first described feedback loop of the Arabidopsis circadian clock is based on reciprocal
regulation between TIMING OF CAB EXPRESSION 1 (TOC1) and CIRCADIAN CLOCK …

The short-period mutant, toc1-1, alters circadian clock regulation of multiple outputs throughout development in Arabidopsis thaliana

DE Somers, AAR Webb, M Pearson, SA Kay - Development, 1998 - journals.biologists.com
The coordination of developmental and physiological events with environmental signals is
facilitated by the action of the circadian clock. Here we report a new set of circadian clock …

Molecular basis of seasonal time measurement in Arabidopsis

MJ Yanovsky, SA Kay - Nature, 2002 - nature.com
Several organisms have evolved the ability to measure daylength, or photoperiod, allowing
them to adjust their development in anticipation of annual seasonal changes. Daylength …